N'-(4-(3,5,6-trichloropyridin-2-yloxy)benzylidene)-4-(1Hindol-3-yl)butanehydrazide

Base Information

• Chemical Name: N'-(4-(3,5,6-trichloropyridin-2-yloxy)benzylidene)-4-(1Hindol-3-yl)butanehydrazide
• CAS No.: 1449036-06-9
• Molecular Formula: C₂₄H₁₉Cl₃N₄O₂
• Molecular Weight: 501.799
• Mol file: 1449036-06-9.mol

Synonyms:N'-(4-(3,5,6-trichloropyridin-2-yloxy)benzylidene)-4-(1Hindol-3-yl)butanehydrazide

Chemical Property of N'-(4-(3,5,6-trichloropyridin-2-yloxy)benzylidene)-4-(1Hindol-3-yl)butanehydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N'-(4-(3,5,6-trichloropyridin-2-yloxy)benzylidene)-4-(1Hindol-3-yl)butanehydrazide

There total 2 articles about N'-(4-(3,5,6-trichloropyridin-2-yloxy)benzylidene)-4-(1Hindol-3-yl)butanehydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 4-(1H-indol-3-yl) butanoate (49850-32-0) → N'-(4-(3,5,6-trichloropyridin-2-yloxy)benzylidene)-4-(1Hindol-3-yl)butanehydrazide (1449036-06-9)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / water; ethanol / 5 h / Reflux

2: ethanol / Reflux

With hydrazine hydrate; In ethanol; water;

DOI:10.1016/j.ejmech.2013.05.024

Reference yield:

4-indol-3-yl-butyric acid (133-32-4) → N'-(4-(3,5,6-trichloropyridin-2-yloxy)benzylidene)-4-(1Hindol-3-yl)butanehydrazide (1449036-06-9)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid / 3 h / Reflux

2: hydrazine hydrate / water; ethanol / 5 h / Reflux

3: ethanol / Reflux

With sulfuric acid; hydrazine hydrate; In ethanol; water;

DOI:10.1016/j.ejmech.2013.05.024

Reference yield: 84.0%

N'-(4-(3,5,6-trichloropyridin-2-yloxy)benzylidene)-4-(1Hindol-3-yl)butanehydrazide (1449036-06-9) → 5-(3-(1H-indol-3-yl)propyl)-2-(4-(3,5,6-trichloropyridin-2-yloxy)phenyl)-1,3,4-oxadiazole (1449036-28-5)

Guidance literature:

With [bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃;

DOI:10.1016/j.ejmech.2013.05.024

upstream raw materials:

ethyl 4-(1H-indol-3-yl) butanoate

4-indol-3-yl-butyric acid

Downstream raw materials:

5-(3-(1H-indol-3-yl)propyl)-2-(4-(3,5,6-trichloropyridin-2-yloxy)phenyl)-1,3,4-oxadiazole