2-(4-bromophenyl)-N-phenylacetamide

Base Information

• Chemical Name: 2-(4-bromophenyl)-N-phenylacetamide
• CAS No.: 85274-93-7
• Molecular Formula: C₁₄H₁₂BrNO
• Molecular Weight: 290.159
• Mol file: 85274-93-7.mol

Synonyms:2-(4-bromophenyl)-N-phenylacetamide

Chemical Property of 2-(4-bromophenyl)-N-phenylacetamide

Chemical Property:

Purity/Quality:

2-(4-BROMOPHENYL)-N-PHENYLACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-bromophenyl)-N-phenylacetamide

There total 12 articles about 2-(4-bromophenyl)-N-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

cis-2,3-epoxy-3-(p-bromophenyl)propanenitrile + aniline (62-53-3) → 2-(4-bromophenyl)-N-phenylacetamide (85274-93-7)

Guidance literature:

With boron trifluoride diethyl etherate; In 1,4-dioxane; at 190 ℃; for 0.5h; Reagent/catalyst; Temperature; Solvent; Time; Concentration; Catalytic behavior; Microwave irradiation; Green chemistry;

DOI:10.1039/c9ob02428j

Reference yield: 69.0%

aniline (62-53-3) + 2-(4-bromophenyl)-acetic acid (1878-68-8) → 2-(4-bromophenyl)-N-phenylacetamide (85274-93-7)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 3.5h;

Reference yield: 68.0%

oxalyl dichloride (79-37-8) + 2-(4-bromophenyl)-acetic acid (1878-68-8) → 2-(4-bromophenyl)-N-phenylacetamide (85274-93-7)

Guidance literature:

With triethylamine; aniline; In dichloromethane; N,N-dimethyl-formamide;

upstream raw materials:

2-(4-bromophenyl)-acetic acid

4-Bromophenylacetonitrile

3-(4-bromo-phenyl)-2-thioxo-propionic acid

3-(4-bromo-phenyl)-2-hydroxyimino-propionic acid

Downstream raw materials:

3-(4-Bromo-phenyl)-2-chloro-quinoline

N-[[4'-[2-oxo-2-(phenylamino)ethyl][1,1'-biphenyl]-4-yl]sulfonyl]-D-valine 1,1-dimethylethyl ester

N₁-phenyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide

{2-[3-(4-Bromo-phenyl)-quinolin-2-ylsulfanyl]-ethyl}-dimethyl-amine