(2S,3S)-methyl 2-(tert-butoxycarbonylamino)-4-(4-methoxyphenyl)-3-methyl-4-oxobutanoate

Base Information

Chemical Name:(2S,3S)-methyl 2-(tert-butoxycarbonylamino)-4-(4-methoxyphenyl)-3-methyl-4-oxobutanoate
CAS No.:164912-22-5
Molecular Formula:C₁₈H₂₅NO₆
Molecular Weight:351.4
Hs Code.:

Synonyms:(2S,3S)-methyl 2-(tert-butoxycarbonylamino)-4-(4-methoxyphenyl)-3-methyl-4-oxobutanoate

Suppliers and Price of (2S,3S)-methyl 2-(tert-butoxycarbonylamino)-4-(4-methoxyphenyl)-3-methyl-4-oxobutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S)-methyl 2-(tert-butoxycarbonylamino)-4-(4-methoxyphenyl)-3-methyl-4-oxobutanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S)-methyl 2-(tert-butoxycarbonylamino)-4-(4-methoxyphenyl)-3-methyl-4-oxobutanoate

There total 4 articles about (2S,3S)-methyl 2-(tert-butoxycarbonylamino)-4-(4-methoxyphenyl)-3-methyl-4-oxobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 13139-86-1
4-methoxyphenyl magnesium bromide

: 164912-07-6
(3S,4S)-1-(tert-butoxycarbonyl)-3-methyl-4-(methoxycarbonyl)azetidin-2-one

: 164912-22-5
(2S,3S)-methyl 2-(tert-butoxycarbonylamino)-4-(4-methoxyphenyl)-3-methyl-4-oxobutanoate

Guidance literature:: In tetrahydrofuran; at -40 ℃;
DOI:10.1021/jo981574d

Reference yield:

: 165036-27-1
(2S,3S)-3-Methyl-4-oxo-azetidine-2-carboxylic acid methyl ester

: 164912-22-5
(2S,3S)-methyl 2-(tert-butoxycarbonylamino)-4-(4-methoxyphenyl)-3-methyl-4-oxobutanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.46 g / 4-(dimethylamino)pyridine / acetonitrile / 16 h

2: 75 percent / tetrahydrofuran / -40 °C

With dmap; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jo981574d

Reference yield:

: 221664-98-8
(3S,4S)-3-methyl-4-(methoxycarbonyl)-1-(4-methoxyphenyl)azetidin-2-one

: 164912-22-5
(2S,3S)-methyl 2-(tert-butoxycarbonylamino)-4-(4-methoxyphenyl)-3-methyl-4-oxobutanoate

Guidance literature:: Multi-step reaction with 3 steps

1: (NH₄)2Ce(NO₃)6 / H₂O; acetonitrile / 0.5 h / -10 °C

2: 1.46 g / 4-(dimethylamino)pyridine / acetonitrile / 16 h

3: 75 percent / tetrahydrofuran / -40 °C

With dmap; ammonium cerium(IV) nitrate; In tetrahydrofuran; water; acetonitrile;
DOI:10.1021/jo981574d