H-D-METYR-OH HCL

Base Information

• Chemical Name: H-D-METYR-OH HCL
• CAS No.: 178357-84-1
• Molecular Formula: C10H13 N O3
• Molecular Weight: 195.218
• Mol file: 178357-84-1.mol

Synonyms:N-Methyl-D-tyrosin;N-methyl-D-tyrosine;Ephinine hydrochloride;D-N-methyltyrosine;N-Methyldopamine hydrochloride;3,4-Dihydroxyphenylethylmethylamine hydrochloride;EPININE HCl;3,4-dihydroxyphenethylmethylammonium chloride;Methyldopamine hydrochloride;D-methyltyrosine;N-Me-D-Tyr-OH;Epinine hydrochloride;

Chemical Property of H-D-METYR-OH HCL

Chemical Property:

• PSA: 69.56000
• LogP: 0.99820
• Storage Temp.: Store at RT.

Purity/Quality:

99% ^*data from raw suppliers

N-Methyl-D-Tyrosine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Methyl-D-Tyrosine Hydrochloride is an amino acid that is useful analytical compound.

Technology Process of H-D-METYR-OH HCL

There total 8 articles about H-D-METYR-OH HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

N-methyl-D-phenylalanine (56564-52-4) → N-methyl-D-tyrosine (178357-84-1)

Guidance literature:

With aluminium trichloride; dihydrogen peroxide; Ambient temperature;

DOI:10.1016/S0040-4039(99)00193-8

Reference yield:

(3R,6R)-1,4-Dimethyl-3-[4-(3-methyl-but-2-enyloxy)-benzyl]-6-methylsulfanyl-piperazine-2,5-dione → N-methyl-L-tyrosine (537-49-5) + N-methyl-D-tyrosine (178357-84-1)

Guidance literature:

With hydrogenchloride; at 110 ℃; for 12h; sealed;

Reference yield:

bisebromoamide (1191115-30-6) → 2,2'-dimethylcystine + L-alanin (56-41-7,25191-17-7,18875-37-1) + (R)-leucine (328-38-1,21675-61-6,25248-98-0,70-45-1) + N-Methyl-L-phenylalanine (2566-30-5) + 2-(1-oxo-propyl)pyrrolidine (1226127-60-1) + 4-methylproline (3005-85-4) + N-methyl-D-tyrosine (178357-84-1)

Guidance literature:

With hydrogenchloride; water; at 110 ℃; for 72h; Sealed vessel;

DOI:10.1016/j.tet.2010.11.106

upstream raw materials:

N,O-diMe-D-Tyr

N-methyl-D-phenylalanine

1,4-dimethyl-3-(p-hydroxy)benzyl-2,5-piperazinedione

(S)-3-(4-Methoxymethoxy-benzyl)-1,4-dimethyl-piperazine-2,5-dione

Downstream raw materials:

(S)-2-{[(R)-2-(Benzyloxycarbonyl-methyl-amino)-3-(3,5-dichloro-4-hydroxy-phenyl)-propionyl]-methyl-amino}-3-(3,5-dibromo-4-hydroxy-phenyl)-propionic acid methyl ester

(9S,12R)-12-(Benzyloxycarbonyl-methyl-amino)-5-bromo-16,17-dichloro-4-hydroxy-10-methyl-11-oxo-2-oxa-10-aza-tricyclo[12.2.2.1^3,7]nonadeca-1⁽¹⁷⁾,3⁽¹⁹⁾,4,6,14⁽¹⁸⁾,15-hexaene-9-carboxylic acid methyl ester

(S)-2-{[(R)-2-(Benzyloxycarbonyl-methyl-amino)-3-(4-hydroxy-phenyl)-propionyl]-methyl-amino}-3-(3,5-dibromo-4-hydroxy-phenyl)-propionic acid methyl ester

Refernces

• 1、 Okano, Tomoki,Sano, Tomoharu,Kaya, Kunimitsu. "Micropeptin T-20, a novel phosphate-containing cyclic depsipeptide from the cyanobacterium Microcystis aeruginosa". . p. 2379 - 2382. Retrieved 1999.
• 2、 Yonezawa, Yasuchika. "Total syntheses of naturally occurring bis(methylthio)silvatin and its three stereoisomers". . p. 1151 - 1159. Retrieved 2007/10/03.