C₇H₆F₃N

Base Information

Chemical Name:C₇H₆F₃N
CAS No.:1445796-44-0
Molecular Formula:C₇H₆F₃N
Molecular Weight:161.127
Hs Code.:

C<sub>7</sub>H<sub>6</sub>F<sub>3</sub>N

Synonyms:C₇H₆F₃N

Suppliers and Price of C₇H₆F₃N

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₇H₆F₃N

Chemical Property:

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Technology Process of C₇H₆F₃N

There total 7 articles about C₇H₆F₃N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1445796-43-9
C₁₂H₁₄F₃NO₂

: 1445796-44-0
C₇H₆F₃N

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;

Reference yield:

: 633327-22-7
5-bromo-2,3-difluorobenzaldehyde

: 1445796-44-0
C₇H₆F₃N

Guidance literature:: Multi-step reaction with 6 steps

1: sodium tetrahydroborate / methanol / 2.5 h / 0 - 20 °C

2: triethylamine / tetrahydrofuran / 2 h / 0 - 20 °C

3: caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos / 1,4-dioxane / 100 °C

4: sodium tetrahydroborate / tetrahydrofuran / 20 °C

5: diethylamino-sulfur trifluoride / dichloromethane / 2 h / -78 - 20 °C / Inert atmosphere

6: trifluoroacetic acid / dichloromethane / 20 °C

With sodium tetrahydroborate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; diethylamino-sulfur trifluoride; caesium carbonate; triethylamine; trifluoroacetic acid; XPhos; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane;

Reference yield:

: 2646-91-5
2,3-difluorobenzaldehyde

: 1445796-44-0
C₇H₆F₃N

Guidance literature:: Multi-step reaction with 7 steps

1: N-Bromosuccinimide; sulfuric acid / 4 h / 60 °C / Inert atmosphere

2: sodium tetrahydroborate / methanol / 2.5 h / 0 - 20 °C

3: triethylamine / tetrahydrofuran / 2 h / 0 - 20 °C

4: caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos / 1,4-dioxane / 100 °C

5: sodium tetrahydroborate / tetrahydrofuran / 20 °C

6: diethylamino-sulfur trifluoride / dichloromethane / 2 h / -78 - 20 °C / Inert atmosphere

7: trifluoroacetic acid / dichloromethane / 20 °C

With sodium tetrahydroborate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-Bromosuccinimide; diethylamino-sulfur trifluoride; sulfuric acid; caesium carbonate; triethylamine; trifluoroacetic acid; XPhos; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane;