N-(tert-butyldiphenylsilyl) (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine

Base Information

• Chemical Name: N-(tert-butyldiphenylsilyl) (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine
• CAS No.: 1356395-35-1
• Molecular Formula: C₂₆H₃₂BrNO₂SSi
• Molecular Weight: 530.601
• Mol file: 1356395-35-1.mol

Synonyms:N-(tert-butyldiphenylsilyl) (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine

Chemical Property of N-(tert-butyldiphenylsilyl) (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine

Chemical Property:

Purity/Quality:

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Technology Process of N-(tert-butyldiphenylsilyl) (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine

There total 1 articles about N-(tert-butyldiphenylsilyl) (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

N-(tert-butyldiphenylsilyl)-S,S-dimethylsulfoximine (1069070-10-5) + 2-bromo-1-(bromomethyl)-4-methoxybenzene (54788-18-0) → N-(tert-butyldiphenylsilyl) (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine (1356395-35-1)

Guidance literature:

N-(tert-butyldiphenylsilyl)-S,S-dimethylsulfoximine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.333333h; Inert atmosphere;

2-bromo-1-(bromomethyl)-4-methoxybenzene; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1055/s-0030-1260260

Reference yield: 87.0%

N-(tert-butyldiphenylsilyl) (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine (1356395-35-1) → (2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine (1356395-36-2)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1055/s-0030-1260260

upstream raw materials:

N-(tert-butyldiphenylsilyl)-S,S-dimethylsulfoximine

2-bromo-1-(bromomethyl)-4-methoxybenzene

Downstream raw materials:

(2-bromo-4-methoxyphenyl)ethyl methyl sulfoximine

Refernces