2-methoxy-5-ethynylpyrimidine

Base Information

Chemical Name:2-methoxy-5-ethynylpyrimidine
CAS No.:1059705-07-5
Molecular Formula:C₇H₆N₂O
Molecular Weight:134.137
Hs Code.:

Synonyms:2-methoxy-5-ethynylpyrimidine

Suppliers and Price of 2-methoxy-5-ethynylpyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-methoxy-5-ethynylpyrimidine

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-methoxy-5-ethynylpyrimidine

There total 4 articles about 2-methoxy-5-ethynylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 67-56-1
methanol

: 2-fluoro-5-((trimethylsilyl)ethynyl)pyrimidine

: 1059705-07-5
2-methoxy-5-ethynylpyrimidine

Guidance literature:: With potassium hydroxide; In dichloromethane; at 20 ℃; for 3h;

Reference yield: 60.0%

: 1059705-06-4
2-methoxy-5-(trimethylsilylethynyl)pyrimidine

: 1059705-07-5
2-methoxy-5-ethynylpyrimidine

Guidance literature:: With water; potassium hydroxide; In tetrahydrofuran; methanol; at 0 ℃; for 0.25h;
DOI:10.1002/jhet.2122

Reference yield:

: 14001-66-2
5-bromo-2-methoxypyrimidine

: 1059705-07-5
2-methoxy-5-ethynylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) iodide; triethylamine / bis-triphenylphosphine-palladium(II) chloride / water; ethyl acetate / 16 h / 60 °C

2: potassium fluoride / water; N,N-dimethyl-formamide / 1 h / 0 °C

With potassium fluoride; copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In water; ethyl acetate; N,N-dimethyl-formamide;