2-Chloro-5-methylnicotinic acid

Base Information

Chemical Name:2-Chloro-5-methylnicotinic acid
CAS No.:66909-30-6
Molecular Formula:C7H6ClNO2
Molecular Weight:171.583
Hs Code.:2933399090
European Community (EC) Number:801-106-7
DSSTox Substance ID:DTXSID80495834
Wikidata:Q72454373
Mol file:66909-30-6.mol

Synonyms:2-Chloro-5-methylnicotinic acid;66909-30-6;2-Chloro-5-methylpyridine-3-carboxylic acid;MFCD07375371;2-Chloro-5-methyl-nicotinic acid;2-Chloro-5-methylnicotinicacid;2-Chloro-5-methylpyridine-3-carboxylicacid;2-chloro-5-methyl-pyridine-3-carboxylic acid;3-Pyridinecarboxylic acid, 2-chloro-5-methyl-;SCHEMBL3041660;DTXSID80495834;HGTOSTXLRLIKCJ-UHFFFAOYSA-N;BCP16113;AKOS006287516;AB41816;CS-W017642;DS-1020;AC-33277;SY107216;TS-02335;2-Chloro-5-methylnicotinic acid, AldrichCPR;A8998;AM20061774;FT-0681661;EN300-127014;Z1198173148

Suppliers and Price of 2-Chloro-5-methylnicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-5-methylnicotinic acid
50mg
$ 45.00

TRC
2-Chloro-5-methylnicotinic acid
100mg
$ 90.00

Sigma-Aldrich
2-Chloro-5-methylnicotinic acid Aldrich
1g
$ 615.00

Matrix Scientific
2-Chloro-5-methylnicotinic acid
1g
$ 87.00

Matrix Scientific
2-Chloro-5-methylnicotinic acid
5g
$ 385.00

Matrix Scientific
2-Chloro-5-methylnicotinic acid
500mg
$ 57.00

Crysdot
2-Chloro-5-methylnicotinic acid 97%
5g
$ 294.00

Chemenu
2-Chloro-5-methylnicotinic acid 97%
5g
$ 363.00

Biosynth Carbosynth
2-Chloro-5-methylnicotinic acid
250 mg
$ 75.00

Biosynth Carbosynth
2-Chloro-5-methylnicotinic acid
1 g
$ 180.00

Total 49 raw suppliers

Chemical Property of 2-Chloro-5-methylnicotinic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.579
Boiling Point:331.175 °C at 760 mmHg
Flash Point:154.089 °C
PSA：50.19000
Density:1.39 g/cm³
LogP:1.74160
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:171.0087061
Heavy Atom Count:11
Complexity:163

Purity/Quality:

99%, ^*data from raw suppliers

2-Chloro-5-methylnicotinic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(N=C1)Cl)C(=O)O

Technology Process of 2-Chloro-5-methylnicotinic acid

There total 6 articles about 2-Chloro-5-methylnicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 65169-43-9
2-chloro-5-methylnicotinic acid methyl ester

: 66909-30-6
2-chloro-5-methyl-3-pyridinecarboxylic acid

Guidance literature:: With methanol; sodium hydroxide; water; at 20 ℃; for 2h;

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: 66909-30-6
2-chloro-5-methyl-3-pyridinecarboxylic acid

Guidance literature:: With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

2-chloro-5-methylpyridine; In tetrahydrofuran; hexane; at -78 ℃; for 2.5h;

carbon dioxide; With hydrogenchloride; water; In tetrahydrofuran; hexane; at 20 ℃;