(2Z)-2-{[(2-amino-1,3-thiazol-4-yl)methoxy]imino}-N-hydroxy-N-methyl-2-phenylethanimidamide

Base Information

Chemical Name:(2Z)-2-{[(2-amino-1,3-thiazol-4-yl)methoxy]imino}-N-hydroxy-N-methyl-2-phenylethanimidamide
CAS No.:1446194-06-4
Molecular Formula:C₁₃H₁₅N₅O₂S
Molecular Weight:305.36
Hs Code.:

Synonyms:(2Z)-2-{[(2-amino-1,3-thiazol-4-yl)methoxy]imino}-N-hydroxy-N-methyl-2-phenylethanimidamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2Z)-2-{[(2-amino-1,3-thiazol-4-yl)methoxy]imino}-N-hydroxy-N-methyl-2-phenylethanimidamide

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Technology Process of (2Z)-2-{[(2-amino-1,3-thiazol-4-yl)methoxy]imino}-N-hydroxy-N-methyl-2-phenylethanimidamide

There total 2 articles about (2Z)-2-{[(2-amino-1,3-thiazol-4-yl)methoxy]imino}-N-hydroxy-N-methyl-2-phenylethanimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1427201-45-3
(2Z)-{[(2-amino-1,3-thiazol-4-yl)methoxy]imino}(phenyl)acetonitrile

: 4229-44-1
N-methylhydroxyamine hydrochloride

: 1446194-06-4
(2Z)-2-{[(2-amino-1,3-thiazol-4-yl)methoxy]imino}-N-hydroxy-N-methyl-2-phenylethanimidamide

Guidance literature:: With caesium carbonate; In water; isopropyl alcohol; at 85 ℃; for 2h;

Reference yield:

: 7541-02-8
(Z)-2-(hydroxyimino)-2-phenylacetonitrile

: 1446194-06-4
(2Z)-2-{[(2-amino-1,3-thiazol-4-yl)methoxy]imino}-N-hydroxy-N-methyl-2-phenylethanimidamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium iodide; caesium carbonate / acetonitrile; N,N-dimethyl-formamide / 20 °C

2: caesium carbonate / isopropyl alcohol; water / 2 h / 85 °C

With caesium carbonate; potassium iodide; In water; N,N-dimethyl-formamide; isopropyl alcohol; acetonitrile;