5-amino-1-β-D-ribofuranosylimidazole-4-

Base Information

Chemical Name:5-amino-1-β-D-ribofuranosylimidazole-4-
CAS No.:119827-69-9
Molecular Formula:C₁₅H₁₇IN₄O₅
Molecular Weight:460.228
Hs Code.:

5-amino-1-β-D-ribofuranosylimidazole-4-<N-(p-iodophenyl)-carboxamide>

Synonyms:5-amino-1-β-D-ribofuranosylimidazole-4-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-amino-1-β-D-ribofuranosylimidazole-4-

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Technology Process of 5-amino-1-β-D-ribofuranosylimidazole-4-

There total 5 articles about 5-amino-1-β-D-ribofuranosylimidazole-4- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 119827-68-8
5-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazole-4-

: 119827-69-9
5-amino-1-β-D-ribofuranosylimidazole-4-

Guidance literature:: With ammonium hydroxide; In methanol; Ambient temperature; overnight;
DOI:10.1002/jhet.5570250512

Reference yield:

: 53459-70-4
N-[5-amino-1-(tri-O-acetyl-β-D-ribofuranosyl)-1H-imidazole-4-carbonyloxy]-succinimide

: 119827-69-9
5-amino-1-β-D-ribofuranosylimidazole-4-

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / dimethylformamide / heated, bath temp. 105 deg C, overnight

2: 74 percent / NH₄OH / methanol / Ambient temperature; overnight

With ammonium hydroxide; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570250512

Reference yield:

: 53459-69-1
5-amino-1-(2,3,5-tris-O-acetyl-β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid

: 119827-69-9
5-amino-1-β-D-ribofuranosylimidazole-4-

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) dicyclohexylcarbodiimide; 2.) acetic acid / 1.) DMF, room temp., overnight; 2.) 5 h

2: 78 percent / dimethylformamide / heated, bath temp. 105 deg C, overnight

3: 74 percent / NH₄OH / methanol / Ambient temperature; overnight

With ammonium hydroxide; acetic acid; dicyclohexyl-carbodiimide; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570250512