53459-70-4 Usage
Uses
Used in Pharmaceutical Industry:
N-Succinimidyl-5-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazole-4-carboxylate is used as a key intermediate for the synthesis of purine-based drugs for the treatment of various diseases. Its protected structure facilitates the development of novel therapeutic agents with improved efficacy and reduced side effects.
Used in Chemical Research:
In the field of chemical research, N-Succinimidyl-5-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazole-4-carboxylate serves as a valuable compound for studying the chemical properties and reactivity of purine metabolites. This knowledge can be applied to design new synthetic routes and develop innovative applications in various industries.
Used in Biochemical Applications:
N-Succinimidyl-5-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazole-4-carboxylate is also utilized in biochemical applications, where it can be employed as a building block for the construction of complex nucleotide analogs and other biologically relevant molecules. These molecules can be used in the development of new diagnostic tools, imaging agents, and therapeutics targeting specific biological pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 53459-70-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,4,5 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 53459-70:
(7*5)+(6*3)+(5*4)+(4*5)+(3*9)+(2*7)+(1*0)=134
134 % 10 = 4
So 53459-70-4 is a valid CAS Registry Number.
53459-70-4Relevant academic research and scientific papers
Synthesis of Guanosines and Deoxyguanosines from 5-amino-1-(β-D-ribofuranosyl)imidazole-4-carboxamide ('AICA-riboside')
Bleasdale, Christine,Ellwood, Simon B.,Golding, Bernard T.,Slaich, Pritpal K.,Taylor, Oonah J.,Watson, William P.
, p. 2859 - 2866 (2007/10/02)
Methods are described for the synthesis of 15N-labelled guanosines and deoxyguanosines, suitable for incorporation into oligonucleotides.The 15N is located at N-1 (e.g. guanosine 1a and deoxyguanosine 1b> or at the NH2 (e.g. guanosine 1
Synthesis and biodistribution of p-iodophenyl analogues of a naturally occurring imidazole ribonucleoside
Suggs,Srivastava
, p. 1331 - 1335 (2007/10/02)
A model iodophenyl imidazole ribonucleoside has been synthesized to study biodistribution properties in laboratory animals. The key intermediate 5-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazole-4-[N-(p-io dophenyl)carboxamide] (5) was synthesized
