2-[Methyl-(3R)-3-pyrrolidinylamino]-ethanol

Base Information

Chemical Name:2-[Methyl-(3R)-3-pyrrolidinylamino]-ethanol
CAS No.:917357-86-9
Molecular Formula:C₇H₁₆N₂O
Molecular Weight:144.217
Hs Code.:
Mol file:917357-86-9.mol

Synonyms:(R)-2-(methyl(pyrrolidin-3-yl)amino)ethanol;2-[Methyl-(3R)-3-pyrrolidinylamino]-ethanol;

Suppliers and Price of 2-[Methyl-(3R)-3-pyrrolidinylamino]-ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 13 raw suppliers

Chemical Property of 2-[Methyl-(3R)-3-pyrrolidinylamino]-ethanol

Chemical Property:

Vapor Pressure:0.00265mmHg at 25°C
PSA：35.50000
LogP:-0.39880

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-[Methyl-(3R)-3-pyrrolidinylamino]-ethanol

There total 5 articles about 2-[Methyl-(3R)-3-pyrrolidinylamino]-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.6%

: 917357-85-8,1353979-31-3,1353999-62-8
benzyl (3R)-3-[(2-hydroxyethyl)(methyl)amino]pyrrolidine-1-carboxylate

: 917357-86-9
2-{methyl[(3R)-pyrrolidin-3-yl]amino}ethanol

Guidance literature:: With hydrogen; palladium hydroxide on carbon; In methanol; at 40 ℃; for 24h; under 2068.65 Torr;

Reference yield:

: 638217-49-9
benzyl (3R)-3-[(tert-butoxycarbonyl)(methyl)amino]pyrrolidine-1-carboxylate

: 917357-86-9
2-{methyl[(3R)-pyrrolidin-3-yl]amino}ethanol

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogenchloride; methanol / 0 - 10 °C

2: potassium carbonate / acetonitrile / 20 °C

3: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / -40 - -10 °C

4: hydrogen / palladium hydroxide on carbon / methanol / 24 h / 40 °C / 2068.65 Torr

With hydrogenchloride; methanol; lithium aluminium tetrahydride; hydrogen; potassium carbonate; palladium hydroxide on carbon; In tetrahydrofuran; methanol; acetonitrile;

Reference yield:

: 917357-84-7
benzyl (3R)-3-[(2-ethoxy-2-oxo-ethyl)(methyl)amino]pyrrolidine-1-carboxylate

: 917357-86-9
2-{methyl[(3R)-pyrrolidin-3-yl]amino}ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / -40 - -10 °C

2: hydrogen / palladium hydroxide on carbon / methanol / 24 h / 40 °C / 2068.65 Torr

With lithium aluminium tetrahydride; hydrogen; palladium hydroxide on carbon; In tetrahydrofuran; methanol;