3-(Methylamino)-1-pyrrolidinecarboxylic acid benzyl ester

Base Information

Chemical Name:3-(Methylamino)-1-pyrrolidinecarboxylic acid benzyl ester
CAS No.:917357-83-6
Molecular Formula:C13H18 N2 O2 . Cl H
Molecular Weight:270.759
Hs Code.:2933990090
Mol file:917357-83-6.mol

Synonyms:BENZYL 3-(METHYLAMINO)PYRROLIDINE-1-CARBOXYLATE;(3R)-3-(Methylamino)-1-Pyrrolidinecarboxylic Acid Phenylmethyl Ester Hydrochloride (1:1);3-(METHYLAMINO)-1-PYRROLIDINECARBOXYLIC ACID BENZYL ESTER;

Suppliers and Price of 3-(Methylamino)-1-pyrrolidinecarboxylic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Benzyl3-(methylamino)pyrrolidine-1-carboxylate 97%
1g
$ 809.00

American Custom Chemicals Corporation
3-METHYLAMINO PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER 95.00%
5MG
$ 496.76

Total 16 raw suppliers

Chemical Property of 3-(Methylamino)-1-pyrrolidinecarboxylic acid benzyl ester

Chemical Property:

Vapor Pressure:2.49E-05mmHg at 25°C
PSA：41.57000
LogP:2.74770

Purity/Quality:

97% ^*data from raw suppliers

Benzyl3-(methylamino)pyrrolidine-1-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(Methylamino)-1-pyrrolidinecarboxylic acid benzyl ester

There total 1 articles about 3-(Methylamino)-1-pyrrolidinecarboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 638217-49-9
benzyl (3R)-3-[(tert-butoxycarbonyl)(methyl)amino]pyrrolidine-1-carboxylate

: 917357-83-6
benzyl (3R)-3-(methylamino)-pyrrolidine-1-carboxylate hydrochloride

Guidance literature:: With hydrogenchloride; methanol; at 0 - 10 ℃;

Reference yield: 88.0%

: 917357-83-6
benzyl (3R)-3-(methylamino)-pyrrolidine-1-carboxylate hydrochloride

: 105-36-2
ethyl bromoacetate

: 917357-84-7
benzyl (3R)-3-[(2-ethoxy-2-oxo-ethyl)(methyl)amino]pyrrolidine-1-carboxylate

Guidance literature:: With potassium carbonate; In acetonitrile; at 20 ℃;

Reference yield:

: 917357-83-6
benzyl (3R)-3-(methylamino)-pyrrolidine-1-carboxylate hydrochloride

: 917357-85-8,1353979-31-3,1353999-62-8
benzyl (3R)-3-[(2-hydroxyethyl)(methyl)amino]pyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 20 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / -40 - -10 °C

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; acetonitrile;