4-chloro-2-[(2,5-dimethoxy-2,5-dihydro-furan-2-ylmethyl)-amino]-5-sulfamoyl-benzoic acid

Base Information

• Chemical Name: 4-chloro-2-[(2,5-dimethoxy-2,5-dihydro-furan-2-ylmethyl)-amino]-5-sulfamoyl-benzoic acid
• CAS No.: 1351169-05-5
• Molecular Formula: C₁₄H₁₇ClN₂O₇S
• Molecular Weight: 392.817
• Mol file: 1351169-05-5.mol

Synonyms:4-chloro-2-[(2,5-dimethoxy-2,5-dihydro-furan-2-ylmethyl)-amino]-5-sulfamoyl-benzoic acid

Chemical Property of 4-chloro-2-[(2,5-dimethoxy-2,5-dihydro-furan-2-ylmethyl)-amino]-5-sulfamoyl-benzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-chloro-2-[(2,5-dimethoxy-2,5-dihydro-furan-2-ylmethyl)-amino]-5-sulfamoyl-benzoic acid

There total 2 articles about 4-chloro-2-[(2,5-dimethoxy-2,5-dihydro-furan-2-ylmethyl)-amino]-5-sulfamoyl-benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methanol (67-56-1) + 4-chloro-2-furfurylamino-5-sulfamoyl-benzoic acid (54-31-9) → 4-chloro-2-[(2,5-dimethoxy-2,5-dihydro-furan-2-ylmethyl)-amino]-5-sulfamoyl-benzoic acid (1351169-05-5)

Guidance literature:

With N,N,N,N-tetraethylammonium tetrafluoroborate; ammonium bromide; at 20 ℃; Electrochemical reaction;

DOI:10.1016/j.tet.2011.10.006

Reference yield: 38.0%

methanol (67-56-1) + 4-chloro-2-furfurylamino-5-sulfamoyl-benzoic acid (54-31-9) → 4-chloro-2-[(2,5-dimethoxy-2,5-dihydro-furan-2-ylmethyl)-amino]-5-sulfamoyl-benzoic acid (1351169-05-5) + 4-chloro-5-sulfamoylanthranilic acid (3086-91-7)

Guidance literature:

With N,N,N,N-tetraethylammonium tetrafluoroborate; ammonium bromide; at 20 ℃; Electrochemical reaction;

DOI:10.1016/j.tet.2011.10.006

Reference yield: 100.0%

4-chloro-2-[(2,5-dimethoxy-2,5-dihydro-furan-2-ylmethyl)-amino]-5-sulfamoyl-benzoic acid (1351169-05-5) → C12H9ClN2O5S (956611-99-7)

Guidance literature:

With water; trifluoroacetic acid; In acetonitrile; at 40 ℃;

DOI:10.1016/j.tet.2011.10.006

upstream raw materials:

methanol

4-chloro-2-furfurylamino-5-sulfamoyl-benzoic acid

Downstream raw materials:

C₁₂H₉ClN₂O₅S