dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate

Base Information

• Chemical Name: dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate
• CAS No.: 1255651-84-3
• Molecular Formula: C₁₈H₂₃IO₁₀
• Molecular Weight: 526.279
• Mol file: 1255651-84-3.mol

Synonyms:dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate

Chemical Property of dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate

There total 4 articles about dimethyl-2,2'-((2-(diacetoxy-λ³-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

peracetic acid (79-21-0) + (2R,2'R)-dimethyl 2,2'-((2-iodo-1,3-phenylene)bis(oxy))dipropanoate (1255651-99-0) → dimethyl-2,2'-((2-(diacetoxy-λ3-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate (1255651-84-3)

Guidance literature:

In acetic acid; at 20 ℃;

DOI:10.1002/anie.201003503

Reference yield: 95.0%

(2R,2'R)-dimethyl 2,2'-((2-iodo-1,3-phenylene)bis(oxy))dipropanoate (1255651-99-0) + acetic acid (64-19-7,77671-22-8) → dimethyl-2,2'-((2-(diacetoxy-λ3-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate (1255651-84-3)

Guidance literature:

With 1-fluoro-4-methyl-1,4-diazoniabicyclo<2.2.2>octane ditetrafluoroborate; In acetonitrile; at 20 ℃; for 5h; Inert atmosphere;

DOI:10.1002/chem.202000927

Reference yield:

2-iodoresorcinol (41046-67-7) → dimethyl-2,2'-((2-(diacetoxy-λ3-iodanyl)-1,3-phenylene)bis(oxy))(2R,2'R)-dipropionate (1255651-84-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere; Darkness

2: Selectfluor / acetonitrile / 5 h / Inert atmosphere

With di-isopropyl azodicarboxylate; Selectfluor; triphenylphosphine; In tetrahydrofuran; acetonitrile;

DOI:10.1002/chem.201603022

upstream raw materials:

peracetic acid

(2R,2'R)-dimethyl 2,2'-((2-iodo-1,3-phenylene)bis(oxy))dipropanoate

2-iodoresorcinol

acetic acid

Downstream raw materials:

(2R,2′R)-2,2′-((2-iodo-1,3-phenylene)bis(oxy))dipropanoic acid

(2R,2'R)-2,2'-((2-iodo-1,3-phenylene)bis(oxy))bis(N-mesitylpropanamide)

(2,6-bis(((R)-1-(mesitylamino)-1-oxopropan-2-yl)oxy)-phenyl)-λ³-iodanediyl diacetate

(S)-1,2-diacetoxy-1-(2,6-difluorophenyl)ethane