(3'S,5'R,6'S)-N⁴-benzoyl-1-(2'-deoxy-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl)cytosine

Base Information

• Chemical Name: (3'S,5'R,6'S)-N⁴-benzoyl-1-(2'-deoxy-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl)cytosine
• CAS No.: 918886-44-9
• Molecular Formula: C₁₉H₁₉N₃O₅
• Molecular Weight: 369.377

Synonyms:(3'S,5'R,6'S)-N⁴-benzoyl-1-(2'-deoxy-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl)cytosine

Chemical Property of (3'S,5'R,6'S)-N⁴-benzoyl-1-(2'-deoxy-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl)cytosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3'S,5'R,6'S)-N⁴-benzoyl-1-(2'-deoxy-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl)cytosine

There total 1 articles about (3'S,5'R,6'S)-N⁴-benzoyl-1-(2'-deoxy-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl)cytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(5'R)-N4-benzoyl-1-[5'-O-(tert-butyldimethylsilyl)-2'-deoxy-3'-C,5'-C-[(5'-C,6'-C-methano)ethano]-α-D-ribofuranosyl]cytosine (440115-08-2) → (3'S,5'R,6'S)-N4-benzoyl-1-(2'-deoxy-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl)cytosine (918886-44-9)

Guidance literature:

With triethylamine hydrofluoride; In pyridine; for 2h;

DOI:10.1002/chem.200600597

Reference yield: 99.0%

(3'S,5'R,6'S)-N4-benzoyl-1-(2'-deoxy-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl)cytosine (918886-44-9) + 4,4’-dimethoxytrityl trifluoromethanesulfonate (239808-67-4) → (3'S,5'R,6'R)-N4-benzoyl-1-{2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl}cytosine (918886-48-3)

Guidance literature:

In pyridine; at 20 ℃; for 4h;

DOI:10.1002/chem.200600597

Reference yield:

(3'S,5'R,6'S)-N4-benzoyl-1-(2'-deoxy-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl)cytosine (918886-44-9) → (5'R,6'S)-N4-benzoyl-1-{3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl}cytosine

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / pyridine / 4 h / 20 °C

2: 71 percent / ethyldiisopropylamine / acetonitrile / 2 h / 20 °C

With N-ethyl-N,N-diisopropylamine; In pyridine; acetonitrile;

DOI:10.1002/chem.200600597

upstream raw materials:

(5'R)-N⁴-benzoyl-1-[5'-O-(tert-butyldimethylsilyl)-2'-deoxy-3'-C,5'-C-[(5'-C,6'-C-methano)ethano]-α-D-ribofuranosyl]cytosine

Downstream raw materials:

(3'S,5'R,6'R)-N⁴-benzoyl-1-{2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl}cytosine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 918886-44-9 (3'S,5'R,6'S)-N⁴-benzoyl-1-(2'-deoxy-3',5'-ethano-5',6'-methano-α-D-ribofuranosyl)cytosine

Send

Send

Metric Ton KG G Pound L ML

Send

Send