(4S)-benzyl-(2S)-tert-butyl-4-methyl-5-oxooxazolidine-3-carboxylic acid allyl ester

Base Information

Chemical Name:(4S)-benzyl-(2S)-tert-butyl-4-methyl-5-oxooxazolidine-3-carboxylic acid allyl ester
CAS No.:1356856-20-6
Molecular Formula:C₁₉H₂₅NO₄
Molecular Weight:331.412
Hs Code.:

Synonyms:(4S)-benzyl-(2S)-tert-butyl-4-methyl-5-oxooxazolidine-3-carboxylic acid allyl ester

Suppliers and Price of (4S)-benzyl-(2S)-tert-butyl-4-methyl-5-oxooxazolidine-3-carboxylic acid allyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S)-benzyl-(2S)-tert-butyl-4-methyl-5-oxooxazolidine-3-carboxylic acid allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S)-benzyl-(2S)-tert-butyl-4-methyl-5-oxooxazolidine-3-carboxylic acid allyl ester

There total 4 articles about (4S)-benzyl-(2S)-tert-butyl-4-methyl-5-oxooxazolidine-3-carboxylic acid allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: (4S)-benzyl-(2S)-tert-butyl-5-oxooxazolidine-3-carboxylic acid allyl ester

: 74-88-4
methyl iodide

: 1356856-20-6
(4S)-benzyl-(2S)-tert-butyl-4-methyl-5-oxooxazolidine-3-carboxylic acid allyl ester

Guidance literature:: (4S)-benzyl-(2S)-tert-butyl-5-oxooxazolidine-3-carboxylic acid allyl ester; With potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -78 ℃;

methyl iodide; In tetrahydrofuran; toluene; at -70 ℃; optical yield given as %de;
DOI:10.1055/s-0031-1289901

Reference yield:

: 630-19-3
pivalaldehyde

: 1356856-20-6
(4S)-benzyl-(2S)-tert-butyl-4-methyl-5-oxooxazolidine-3-carboxylic acid allyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / ethanol; water / 1 h / 20 °C

1.2: 48 h / Dean-Stark trap; Reflux

2.1: boron trifluoride diethyl etherate / dichloromethane / 144 h / 5 °C

3.1: potassium hexamethylsilazane / tetrahydrofuran; toluene / -78 °C

3.2: -70 °C

With boron trifluoride diethyl etherate; potassium hexamethylsilazane; sodium hydroxide; In tetrahydrofuran; ethanol; dichloromethane; water; toluene;
DOI:10.1055/s-0031-1289901

Reference yield:

: Sodium; (S)-2-[2,2-dimethyl-prop-(E)-ylideneamino]-3-phenyl-propionate

: 1356856-20-6
(4S)-benzyl-(2S)-tert-butyl-4-methyl-5-oxooxazolidine-3-carboxylic acid allyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: boron trifluoride diethyl etherate / dichloromethane / 144 h / 5 °C

2.1: potassium hexamethylsilazane / tetrahydrofuran; toluene / -78 °C

2.2: -70 °C

With boron trifluoride diethyl etherate; potassium hexamethylsilazane; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1055/s-0031-1289901