[5-(benzyl-{6-[benzyl-(6-benzyloxycarbonylaminohexanoyl)amino]hexyl}carbamoyl)pentyl]carbamic acid benzyl ester

Base Information

Chemical Name:[5-(benzyl-{6-[benzyl-(6-benzyloxycarbonylaminohexanoyl)amino]hexyl}carbamoyl)pentyl]carbamic acid benzyl ester
CAS No.:428879-79-2
Molecular Formula:C₄₈H₆₂N₄O₆
Molecular Weight:791.043
Hs Code.:

Synonyms:[5-(benzyl-{6-[benzyl-(6-benzyloxycarbonylaminohexanoyl)amino]hexyl}carbamoyl)pentyl]carbamic acid benzyl ester

Suppliers and Price of [5-(benzyl-{6-[benzyl-(6-benzyloxycarbonylaminohexanoyl)amino]hexyl}carbamoyl)pentyl]carbamic acid benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [5-(benzyl-{6-[benzyl-(6-benzyloxycarbonylaminohexanoyl)amino]hexyl}carbamoyl)pentyl]carbamic acid benzyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of [5-(benzyl-{6-[benzyl-(6-benzyloxycarbonylaminohexanoyl)amino]hexyl}carbamoyl)pentyl]carbamic acid benzyl ester

There total 1 articles about [5-(benzyl-{6-[benzyl-(6-benzyloxycarbonylaminohexanoyl)amino]hexyl}carbamoyl)pentyl]carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1947-00-8
6-(benzyloxycarbonylamino)hexanoic acid

: 30070-99-6
N,N'-dibenzyl-1,6-diaminohexane

: 428879-79-2
[5-(benzyl-{6-[benzyl-(6-benzyloxycarbonylaminohexanoyl)amino]hexyl}carbamoyl)pentyl]carbamic acid benzyl ester

Guidance literature:: 6-(benzyloxycarbonylamino)hexanoic acid; With chloroformic acid ethyl ester; triethylamine; In 1,4-dioxane; for 0.5h;

N,N'-dibenzyl-1,6-diaminohexane; In 1,4-dioxane; at 20 ℃; Further stages.;
DOI:10.1021/jm011067f

Reference yield: 90.0%

: 428879-79-2
[5-(benzyl-{6-[benzyl-(6-benzyloxycarbonylaminohexanoyl)amino]hexyl}carbamoyl)pentyl]carbamic acid benzyl ester

: 428879-80-5
6-aminohexanoic acid {6-[(6-aminohexanoyl)benzylamino]hexyl}benzylamide

Guidance literature:: With acetic acid; trifluoroacetic acid; for 2h;
DOI:10.1021/jm011067f

Reference yield:

: 428879-79-2
[5-(benzyl-{6-[benzyl-(6-benzyloxycarbonylaminohexanoyl)amino]hexyl}carbamoyl)pentyl]carbamic acid benzyl ester

: N-[1-{3-[6-({6-[(6-aminohexyl)benzylamino]hexyl}benzylamino)hexylamino]propylcarbamoyl}-2-(4-benzyloxyphenyl)ethyl]butyramide tetratrifluoroacetate

Guidance literature:: Multi-step reaction with 7 steps

1: 90 percent / 30percent HBr; AcOH; CF₃COOH / 2 h

2: 40 percent / 10 M BH₃*MeSMe / bis-(2-methoxy-ethyl) ether / 10 h / 120 °C

3: 35 percent / methanol / 3 h / 0 °C

4: 100 percent / CHCl₃

5: 70 percent / H₂; 40percent aq. NaOH / Raney Ni / ethanol / 6 h / 20 °C / 775.74 Torr

6: 67 percent / methanol / 1 h / 20 °C

7: 100 percent / CH₂Cl₂ / 2 h / 20 °C

With dimethylsulfide borane complex; hydrogen; acetic acid; trifluoroacetic acid; nickel; In methanol; ethanol; dichloromethane; chloroform; diethylene glycol dimethyl ether;
DOI:10.1021/jm011067f