TRANS-METHYL 4-AMINOMETHYL-CYCLOHEXANECARBOXYLATE HCL

Base Information

• Chemical Name: TRANS-METHYL 4-AMINOMETHYL-CYCLOHEXANECARBOXYLATE HCL
• CAS No.: 29275-88-5
• Molecular Formula: C₉H₁₇NO₂*ClH
• Molecular Weight: 207.7
• Hs Code.: 2922499990
• Mol file: 29275-88-5.mol

Synonyms:Cyclohexanecarboxylicacid, 4-(aminomethyl)-, methyl ester, hydrochloride, trans- (8CI,9CI); Methyltrans-4-(aminomethyl)cyclohexanecarboxylate hydrochloride;trans-4-(Aminomethyl)cyclohexanecarboxylic acid methyl ester hydrochloride

Chemical Property of TRANS-METHYL 4-AMINOMETHYL-CYCLOHEXANECARBOXYLATE HCL

Chemical Property:

• Vapor Pressure: 0.00327mmHg at 25°C
• Boiling Point: 278.5°C at 760 mmHg
• Flash Point: 122.2°C
• PSA: 52.32000
• LogP: 2.42680
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Water Solubility.: Soluble in water

Purity/Quality:

98%,99%, ^*data from raw suppliers

trans-Methyl4-(Aminomethyl)cyclohexanecarboxylateHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TRANS-METHYL 4-AMINOMETHYL-CYCLOHEXANECARBOXYLATE HCL

There total 1 articles about TRANS-METHYL 4-AMINOMETHYL-CYCLOHEXANECARBOXYLATE HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) → 4-aminomethylcyclohexanecarboxylic acid methyl ester hydrochloride salt (54640-02-7,29275-88-5)

Guidance literature:

With hydrogenchloride;

Reference yield: 94.0%

2-Amino-5-methylbenzoic acid (2941-78-8) + trans-methyl 4-(aminomethyl)cyclohexane-1-carboxylate hydrochloride salt (29275-88-5) → trans-methyl 4-{[(2-amino-5-methylphenyl)formamido]methyl}cyclohexane-1-carboxylate

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 25 ℃; for 16h;

Reference yield: 93.0%

2,4,6-triphenylpyrylium tetrafluoroborate (448-61-3) + trans-(4-aminomethyl)cyclohexane-1-carboxylic acid methyl ester hydrochloride (29275-88-5) → 1-(((1r,4r)-4-(methoxycarbonyl)cyclohexyl)methyl)-2,4,6-triphenylpyridin-1-ium tetrafluoroborate

Guidance literature:

In ethanol; Reflux;

DOI:10.1021/acs.orglett.1c01959

upstream raw materials:

methanol

Downstream raw materials:

C₃₂H₅₃N₅O₁₂