1-(4-Fluorophenyl)cyclopropanecarboxamide

Base Information

Chemical Name:1-(4-Fluorophenyl)cyclopropanecarboxamide
CAS No.:133284-48-7
Molecular Formula:C₁₀H₁₀FNO
Molecular Weight:179.194
Hs Code.:
DSSTox Substance ID:DTXSID601271789

Synonyms:1-(4-FLUOROPHENYL)CYCLOPROPANECARBOXAMIDE;133284-48-7;SCHEMBL379020;VQEGVEJEUOVINR-UHFFFAOYSA-N;DTXSID601271789;AKOS009162242;AB64475;1-(4-fluorophenyl)cyclopropane carboxamide;Cyclopropanecarboxamide, 1-(4-fluorophenyl)-;1-(4-FLUOROPHENYL)CYCLOPROPANE-1-CARBOXAMIDE;Z300502674

Suppliers and Price of 1-(4-Fluorophenyl)cyclopropanecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 1-(4-Fluorophenyl)cyclopropanecarboxamide

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:179.074642105
Heavy Atom Count:13
Complexity:217

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC1(C2=CC=C(C=C2)F)C(=O)N

Technology Process of 1-(4-Fluorophenyl)cyclopropanecarboxamide

There total 5 articles about 1-(4-Fluorophenyl)cyclopropanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 97009-67-1
1-(4-fluorophenyl)cyclopropane-1-carbonitrile

: 133284-48-7
1-(4-fluorophenyl)cyclopropane-1-carboxamide

Guidance literature:: With sodium hydroxide; dihydrogen peroxide; In water; acetone; at 20 ℃; for 2h; Cooling with ice;
DOI:10.1016/j.bmc.2008.08.065

Reference yield: 81.0%

: 1455028-72-4
N-(2,4-dimethoxybenzyl)-1-(4-fluorophenyl)cyclopropanecarboxamide

: 133284-48-7
1-(4-fluorophenyl)cyclopropane-1-carboxamide

Guidance literature:: With trifluoroacetic acid; at 20 ℃; for 2h;

Reference yield:

: 773100-29-1
1-(4-fluorophenyl)cyclopropane-1-carboxylic acid

: 133284-48-7
1-(4-fluorophenyl)cyclopropane-1-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide; oxalyl dichloride / 0.67 h / 20 °C

2: triethylamine / dichloromethane / 2 h / 0 - 20 °C

3: trifluoroacetic acid / 2 h / 20 °C

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; trifluoroacetic acid; In dichloromethane;