2-bromo-6-nitro-4-phenoxyphenylamine

Base Information

• Chemical Name: 2-bromo-6-nitro-4-phenoxyphenylamine
• CAS No.: 1120334-11-3
• Molecular Formula: C₁₂H₉BrN₂O₃
• Molecular Weight: 309.119
• Mol file: 1120334-11-3.mol

Synonyms:2-bromo-6-nitro-4-phenoxyphenylamine

Chemical Property of 2-bromo-6-nitro-4-phenoxyphenylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-bromo-6-nitro-4-phenoxyphenylamine

There total 4 articles about 2-bromo-6-nitro-4-phenoxyphenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-nitro-4-phenoxyphenylamine (60854-00-4) → 2-bromo-6-nitro-4-phenoxyphenylamine (1120334-11-3)

Guidance literature:

With bromine; In dichloromethane; at 0 ℃; for 2h;

Reference yield:

p-phenoxyacetanilide (6312-87-4) → 2-bromo-6-nitro-4-phenoxyphenylamine (1120334-11-3)

Guidance literature:

Multi-step reaction with 3 steps

1: nitric acid / 2 h / -15 °C

2: sodium hydroxide / methanol / 18 h / 20 °C

3: bromine / dichloromethane / 2 h / 0 °C

With bromine; nitric acid; sodium hydroxide; In methanol; dichloromethane;

Reference yield:

4-phenoxyanilin (139-59-3) → 2-bromo-6-nitro-4-phenoxyphenylamine (1120334-11-3)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 1 h / 0 - 20 °C

2: nitric acid / 2 h / -15 °C

3: sodium hydroxide / methanol / 18 h / 20 °C

4: bromine / dichloromethane / 2 h / 0 °C

With bromine; nitric acid; triethylamine; sodium hydroxide; In methanol; dichloromethane;

upstream raw materials:

2-nitro-4-phenoxyphenylamine

p-phenoxyacetanilide

4-phenoxyanilin

N-(2-nitro-4-phenoxyphenyl)acetamide