<(tert-butoxycarbonyl)amino>-3 hydroxymethyl-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S)

Base Information

Chemical Name:<(tert-butoxycarbonyl)amino>-3 hydroxymethyl-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S)
CAS No.:102192-14-3
Molecular Formula:C₁₈H₂₃N₃O₈
Molecular Weight:409.396
Hs Code.:

Synonyms:<(tert-butoxycarbonyl)amino>-3 hydroxymethyl-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S)

Suppliers and Price of <(tert-butoxycarbonyl)amino>-3 hydroxymethyl-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of <(tert-butoxycarbonyl)amino>-3 hydroxymethyl-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S)

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of <(tert-butoxycarbonyl)amino>-3 hydroxymethyl-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S)

There total 5 articles about <(tert-butoxycarbonyl)amino>-3 hydroxymethyl-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 102192-13-2
<(tert-butoxycarbonyl)amino>-3 (hydroxymethoxymethyl)-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S)

: 102192-14-3
<(tert-butoxycarbonyl)amino>-3 hydroxymethyl-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S)

Guidance literature:: With sodium cyanoborohydride; acetic acid; In tetrahydrofuran; for 1h; Ambient temperature;

Reference yield:

: 7352-64-9
glycine 4-nitrobenzyl ester

: 102192-14-3
<(tert-butoxycarbonyl)amino>-3 hydroxymethyl-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S)

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) magnesium sulfate 2.) triethylamine / 1.) CH₂Cl₂, 30 min, room temp. 2.) CH₂Cl₂, 30 min, reflux

2: 97 percent / hydrazine hydrate / dioxane / 1 h / Ambient temperature

3: 63 percent / tetrahydrofuran / 1 h / Heating

4: 1.) ozone 2.) dimethyl sulfide / 1.) CH₂Cl₂, -70 deg C 2.) CH₂Cl₂, 1 h, room temp.

5: 91 percent / acetic acid, sodium cyanoborohydride / tetrahydrofuran / 1 h / Ambient temperature

With dimethylsulfide; sodium cyanoborohydride; magnesium sulfate; ozone; hydrazine hydrate; acetic acid; triethylamine; In tetrahydrofuran; 1,4-dioxane;

Reference yield:

: 102192-12-1
[(3S,4R)-3-Amino-2-oxo-4-((E)-styryl)-azetidin-1-yl]-acetic acid 4-nitro-benzyl ester

: 102192-14-3
<(tert-butoxycarbonyl)amino>-3 hydroxymethyl-4 oxo-2 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-R,S)

Guidance literature:: Multi-step reaction with 3 steps

1: 63 percent / tetrahydrofuran / 1 h / Heating

2: 1.) ozone 2.) dimethyl sulfide / 1.) CH₂Cl₂, -70 deg C 2.) CH₂Cl₂, 1 h, room temp.

3: 91 percent / acetic acid, sodium cyanoborohydride / tetrahydrofuran / 1 h / Ambient temperature

With dimethylsulfide; sodium cyanoborohydride; ozone; acetic acid; In tetrahydrofuran;