7352-64-9

Upstream product

• 5680-81-9 N-benzyloxycarbonyl-glycine p-nitrobenzyl ester 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 619-73-8 4-nitrobenzyl chloride 
• 56-40-6 glycine 
• 7352-63-8 p-toluenesulfonate de glycinate de p-nitrobenzyle 
• 100-14-1 4-nitrobenzyl chloride 

Downstream Products

• 26054-98-8 N-(N-benzyloxycarbonyl-L-seryl)-glycine-(4-nitro-benzyl ester) 
• 100406-09-5 Benzyloxycarbonyl-DL-alanyl-glycin-p-nitro-benzylester 
• 63349-18-8 C₁₆H₂₅N₂O₈P 
• 53932-38-0 Boc-Pro-Gly-OBzl(NO₂) 
• 102192-11-0 oxo-2 (phenyl-2 vinyl)-4 phtalimido-3 azetidine-1-acetate de p-nitrobenzyle (3-R,S)(4-S,R)(E) 
• 21466-91-1 N^α-benzyloxycarbonyl-N^G-nitroarginylglycine p-nitrobenzyl ester 
• 79105-60-5 [2-(2-Methyl-[1,3]dithian-2-yl)-eth-(Z)-ylideneamino]-acetic acid 4-nitro-benzyl ester 
• 79092-37-8 [2-[1,3]Dithian-2-yl-eth-(Z)-ylideneamino]-acetic acid 4-nitro-benzyl ester 
• 100143-77-9 N-Pyruvoyl-glycin-4-nitro-benzylester 
• 51782-11-7 Z-Cys(-CH2-Ph)-Gly-ONB 
• 23556-78-7 (+)-N-Cbz-L-alanyl-PNB-glycinate 
• 17079-50-4 -glycin-p-nitrobenzylester 
• 17079-53-7 (N-Benzoyl-β-benzyl-α-DL-aspartyl)-glycin-p-nitrobenzylester 
• 17079-49-1 -glycin-p-nitrobenzylester 

Relevant academic research and scientific papers

1-dethia-2-thia-cephalosporanic acids

Novel 1-dethia-2-thia-cephalosporanic acid derivatives of the formula STR1 wherein R is selected from the group consisting of STR2 Ra is an organic radical, Ri and Rj are individually selected from the group consisting of hydrogen, aliphatic, aromatic and heterocycle or taken together with the nitrogen atom to which they are attached form an optionally substituted cycle or Rb NH--, Rb is optionally substituted carbocyclic or heterocyclic aryl, R1 and --COM are as defined in the specification, R4 is hydrogen or methoxy, n2 is 0, 1 or 2 and their non-toxic, pharmaceutically acceptable acid addition salts in racemic or optically active form having antibiotic activity and their preparation and novel intermediates.

Vibrational spectra of N-acetylglycine oligomers. Part 2. - Raman scattering study of selectively C-deuteriated oligomers with polyglycine I- and II-type structures

Selectively C-deuteriated N-acetylglycine trimer and tetramer acid types have been synthesized, and their two crystalline modifications, solid-A and solid-B [which correspond in structure to polyglycine (PG) II and I, respectively] have been prepared. Raman scattering spectra have been measured for a series of these glycine oligomers, and the CH2- and CD2-characteristic modes have been investigated in detail. Assignment of the CH2-characteristic bands to each CH2 group in the oligomers has been carried out successfully. In particular, the results obtained from the CD2 stretch region show that N- and C-terminal glycine residues for the PGI- and PGII-type trimers and tetramers are all in very similar environments and that the glycine residues which are sandwiched between the two terminal residues are also in a similar environment for both the trimers and the tetramers.

Cleavage of Chiral 4-Phenyl-2-Oxazolidinones with TMSI: Application to the Synthesis of Carbacephems

A new technique for cleaving chiral N-substituted 4-phenyl-2-oxazolidinones is described.Thus reaction of a 7-carbacephem with TMSI and HMDS in acetonitrile, followed by DABCO, then aqueous hydrochloric acid gives the carbacephem nucleus, carbon dioxide, and acetophenone.This method allows a more versatile use of 4-phenyl-2-oxazolidinone as a chiral auxiliary and N-protective group in the synthesis of carbacephems. Key Words: trimethylsilyl iodide; chiral auxiliary; 4-phenyl-2-oxazolidinones; carbacephems; beta-lactams

Synthese totale d'isocephemes heterosubstitues en 3

Base promoted reaction of a suitably substituted N-carboxymethyl-azetidinone 9 with carbon disulfide or carbon oxysulfide, leads conveniently to 3-heterosubstituted-2-isocephems in good to excellent yield.