methyl 2-(3-butenyl)-3-benzoylpropionate ethylene ketal

Base Information

• Chemical Name: methyl 2-(3-butenyl)-3-benzoylpropionate ethylene ketal
• CAS No.: 172980-66-4
• Molecular Formula: C₁₇H₂₂O₄
• Molecular Weight: 290.359
• Mol file: 172980-66-4.mol

Synonyms:methyl 2-(3-butenyl)-3-benzoylpropionate ethylene ketal

Chemical Property of methyl 2-(3-butenyl)-3-benzoylpropionate ethylene ketal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-(3-butenyl)-3-benzoylpropionate ethylene ketal

There total 2 articles about methyl 2-(3-butenyl)-3-benzoylpropionate ethylene ketal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-iodobut-1-ene (7766-51-0) + 2-[2-(methoxycarbonyl)ethyl]-2-phenyl-1,3-dioxolane (103632-91-3) → methyl 2-(3-butenyl)-3-benzoylpropionate ethylene ketal (172980-66-4)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, 25 deg C, 5 h, 2.) reflux, 24 h;

DOI:10.1021/jo951576n

Reference yield:

3-benzoylpropionic acid methyl ester (25333-24-8) → methyl 2-(3-butenyl)-3-benzoylpropionate ethylene ketal (172980-66-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / p-TsOH / benzene / Heating

2: 1.) LDA / 1.) THF, 25 deg C, 5 h, 2.) reflux, 24 h

With toluene-4-sulfonic acid; lithium diisopropyl amide; In benzene;

DOI:10.1021/jo951576n

Reference yield: 89.0%

methyl 2-(3-butenyl)-3-benzoylpropionate ethylene ketal (172980-66-4) → methyl 2-(3-butenyl)-3-benzoylpropionate (172980-67-5)

Guidance literature:

With pyridinium p-toluenesulfonate; In diethyl ether; acetone; at 80 ℃; for 12h;

DOI:10.1021/jo951576n

upstream raw materials:

4-iodobut-1-ene

2-[2-(methoxycarbonyl)ethyl]-2-phenyl-1,3-dioxolane

3-benzoylpropionic acid methyl ester

Downstream raw materials:

methyl 2-(3-butenyl)-3-benzoylpropionate

3,5-methano-8-oxatricyclo-7-oxo-4-phenyl<3.2.1.0^1,4>octane

3-(3-butenyl)-1-diazo-5-phenyl-2,5-pentanedione