p-nitrophenyl 3-(2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranosyl)propionate

Base Information

• Chemical Name: p-nitrophenyl 3-(2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranosyl)propionate
• CAS No.: 79360-06-8
• Molecular Formula: C₂₃H₂₇NO₁₃S
• Molecular Weight: 557.532
• Mol file: 79360-06-8.mol

Synonyms:p-nitrophenyl 3-(2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranosyl)propionate

Chemical Property of p-nitrophenyl 3-(2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranosyl)propionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-nitrophenyl 3-(2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranosyl)propionate

There total 2 articles about p-nitrophenyl 3-(2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranosyl)propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + 3-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-1-thio)propionic acid (79360-05-7) → p-nitrophenyl 3-(2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranosyl)propionate (79360-06-8)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1021/jm00144a004

Reference yield:

2,3,4,6-tetra-O-acetylgalactopyranosyl-1-β-pseudothiourea hydrobromide (40591-65-9,51224-13-6,51898-28-3,57030-42-9,106818-92-2) → p-nitrophenyl 3-(2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranosyl)propionate (79360-06-8)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂S₂O₅, K₂CO₃ / acetone / 0.75 h / Ambient temperature

2: 54 percent / dicyclohexylcarbodiimide (DCC) / CH₂Cl₂ / 1 h / Ambient temperature

With potassium disulphite; potassium carbonate; dicyclohexyl-carbodiimide; In dichloromethane; acetone;

DOI:10.1021/jm00144a004

upstream raw materials:

4-nitro-phenol

3-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-1-thio)propionic acid

2,3,4,6-tetra-O-acetylgalactopyranosyl-1-β-pseudothiourea hydrobromide