3-[(2,3,4,6-O-Tetraacetyl-b-D-galactopyranosyl)thio]propionoic acid, 95%

Base Information

• Chemical Name: 3-[(2,3,4,6-O-Tetraacetyl-b-D-galactopyranosyl)thio]propionoic acid, 95%
• CAS No.: 79360-05-7
• Molecular Formula: C17H24 O11 S
• Molecular Weight: 436.43
• Mol file: 79360-05-7.mol

Synonyms:2-Carboxyethyl2,3,4,6-tetra-O-acetyl-1-thio-b-D-galactopyranoside; 3-(2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosylthio)propionicacid

Chemical Property of 3-[(2,3,4,6-O-Tetraacetyl-b-D-galactopyranosyl)thio]propionoic acid, 95%

Chemical Property:

• PSA: 199.03000
• LogP: -0.94580

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-[(2,3,4,6-O-Tetraacetyl-b-D-galactopyranosyl)thio]propionoic acid, 95%

There total 7 articles about 3-[(2,3,4,6-O-Tetraacetyl-b-D-galactopyranosyl)thio]propionoic acid, 95% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3-iodopropanoic acid (141-76-4) + 2,3,4,6-tetra-O-acetylgalactopyranosyl-1-β-pseudothiourea hydrobromide (40591-65-9,51224-13-6,51898-28-3,57030-42-9,106818-92-2) → 3-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-1-thio)propionic acid (79360-05-7)

Guidance literature:

3-iodopropanoic acid; 2,3,4,6-tetra-O-acetylgalactopyranosyl-1-β-pseudothiourea hydrobromide; With potassium carbonate; In water; acetone; at 20 ℃; for 0.75h;

With hydrogenchloride; water; In chloroform; acetone;

DOI:10.1021/bc100030q

Reference yield: 91.0%

3-mercaptopropionic acid (107-96-0) + β-D-galactose peracetate (4163-60-4) → 3-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-1-thio)propionic acid (79360-05-7)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane;

DOI:10.1002/cplu.201300130

Reference yield: 88.0%

D-galactose pentaacetate (25878-60-8) + 3-mercaptopropionic acid (107-96-0) → 3-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-1-thio)propionic acid (79360-05-7)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at 20 ℃; for 4h;

DOI:10.1021/jm040794i

upstream raw materials:

3-iodopropanoic acid

2,3,4,6-tetra-O-acetylgalactopyranosyl-1-β-pseudothiourea hydrobromide

3-mercaptopropionic acid

β-D-galactose peracetate

Downstream raw materials:

p-nitrophenyl 3-(2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranosyl)propionate

1-S-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-3-mercaptopropionic acid pentafluorophenyl ester

2,3,4,6-tetra-O-acetylgalactopyranosyl-1-α-(3'-thiopropionate-O-2,3,5,6-tetrafluorophenyl ester)