tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate

Base Information

Chemical Name:tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate
CAS No.:932398-74-8
Molecular Formula:C₁₄H₁₉NO₃
Molecular Weight:249.31
Hs Code.:

Synonyms:tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate

Suppliers and Price of tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate

There total 1 articles about tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: 1407968-48-2
3-[N-(tert-butoxycarbonyl)-N-(2-iodophenyl)amino]propanal

: 57476-50-3
1-tert-butoxycarbonyl-3-formylindole

: 932398-74-8
tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate

: 179898-00-1
1-tert-butyloxycarbonyl-1,2,3,4-tetrahydro-4-quinolinone

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; triethylamine; In tetrahydrofuran; at 110 ℃; for 24h; chemoselective reaction; Sealed tube;
DOI:10.1021/jo301924e

Reference yield: 72.0%

: 932398-74-8
tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate

: 42599-17-7
(E)-1-iodo-1-octene

: 775-12-2
diphenylsilane

: tert-butyl 4-((octyldiphenylsilyl)oxy)-3,4-dihydroquinoline-1(2H)-carboxylate

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; diisopropylamine; In dichloromethane; at 20 ℃; for 16h; Glovebox; Sealed tube; Inert atmosphere;
DOI:10.1002/chem.201805595

Reference yield:

: 932398-74-8
tert-butyl rac-4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate

: C₂₃H₂₆N₄O₂

Guidance literature:: Multi-step reaction with 2 steps

1: trimethylsilylazide; silver trifluoromethanesulfonate / dichloromethane / 2 h / 20 °C

2: copper(l) iodide; [2,2]bipyridinyl / dichloromethane / 24 h / 20 °C / Sealed tube

With [2,2]bipyridinyl; copper(l) iodide; trimethylsilylazide; silver trifluoromethanesulfonate; In dichloromethane;
DOI:10.1021/acs.orglett.9b01556