ethyl 6-(4-methylbenzyl)-2-(benzyloxy)-4-hydroxynicotinate

Base Information

Chemical Name:ethyl 6-(4-methylbenzyl)-2-(benzyloxy)-4-hydroxynicotinate
CAS No.:1430414-48-4
Molecular Formula:C₂₃H₂₃NO₄
Molecular Weight:377.44
Hs Code.:

Synonyms:ethyl 6-(4-methylbenzyl)-2-(benzyloxy)-4-hydroxynicotinate

Suppliers and Price of ethyl 6-(4-methylbenzyl)-2-(benzyloxy)-4-hydroxynicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 6-(4-methylbenzyl)-2-(benzyloxy)-4-hydroxynicotinate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 6-(4-methylbenzyl)-2-(benzyloxy)-4-hydroxynicotinate

There total 5 articles about ethyl 6-(4-methylbenzyl)-2-(benzyloxy)-4-hydroxynicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1430414-46-2
ethyl 6-(4-methylbenzyl)-4-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylate

: 100-39-0
benzyl bromide

: 1430414-48-4
ethyl 6-(4-methylbenzyl)-2-(benzyloxy)-4-hydroxynicotinate

Guidance literature:: With silver (II) carbonate; In tetrahydrofuran; at 60 ℃; for 8h;
DOI:10.1021/jm400102x

Reference yield:

: 62135-86-8
4'-methylphenylacetoacetic acid ethyl ester

: 1430414-48-4
ethyl 6-(4-methylbenzyl)-2-(benzyloxy)-4-hydroxynicotinate

Guidance literature:: Multi-step reaction with 3 steps

1.1: ammonia / methanol / 8 h / Reflux; Sealed tube

2.1: sodium / ethanol / 1 h

2.2: 96 h / Reflux

3.1: silver (II) carbonate / tetrahydrofuran / 8 h / 60 °C

With silver (II) carbonate; ammonia; sodium; In tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm400102x

Reference yield:

: 2,2-dimethyl-5-(2-(p-tolyl)acetyl)-1,3-dioxane-4,6-dione

: 1430414-48-4
ethyl 6-(4-methylbenzyl)-2-(benzyloxy)-4-hydroxynicotinate

Guidance literature:: Multi-step reaction with 4 steps

1.1: 4 h / Reflux

2.1: ammonia / methanol / 8 h / Reflux; Sealed tube

3.1: sodium / ethanol / 1 h

3.2: 96 h / Reflux

4.1: silver (II) carbonate / tetrahydrofuran / 8 h / 60 °C

With silver (II) carbonate; ammonia; sodium; In tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm400102x