Methyl 2-Chloro-5-iodonicotinate

Base Information

Chemical Name:Methyl 2-Chloro-5-iodonicotinate
CAS No.:78686-83-6
Molecular Formula:C7H5 Cl I N O2
Molecular Weight:297.48
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70377498
Wikidata:Q82166736
Mol file:78686-83-6.mol

Synonyms:Methyl 2-Chloro-5-iodonicotinate;78686-83-6;methyl 2-chloro-5-iodopyridine-3-carboxylate;MFCD06659607;3-Pyridinecarboxylic acid, 2-chloro-5-iodo-, methyl ester;2-chloro-5-iodo-nicotinic acid methyl ester;SCHEMBL1505507;DTXSID70377498;methyl 5-iodo-2-chloronicotinate;methyl-2-chloro-5-iodonicotinate;XJAILSCNCPJQPH-UHFFFAOYSA-N;AKOS005071592;AM804358;SY041325;CS-0081039;FT-0680753;methyl 2-chloro-5-iodo-3-pyridinecarboxylate;EN300-7414292;9Y-0700;J-521988

Suppliers and Price of Methyl 2-Chloro-5-iodonicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Methyl 2-chloro-5-iodonicotinate
100mg
$ 312.00

TRC
Methyl2-chloro-5-iodonicotinate
100mg
$ 45.00

Matrix Scientific
Methyl 2-chloro-5-iodonicotinate >95%
5g
$ 378.00

Matrix Scientific
Methyl 2-chloro-5-iodonicotinate >95%
500mg
$ 77.00

Labseeker
METHYL2-CHLORO-5-IODONICOTINATE 98
5g
$ 462.00

Frontier Specialty Chemicals
Methyl2-chloro-5-iodonicotinate 98%
1g
$ 50.00

Frontier Specialty Chemicals
Methyl2-chloro-5-iodonicotinate 98%
5g
$ 190.00

Crysdot
Methyl2-chloro-5-iodonicotinate 97%
10g
$ 386.00

Crysdot
Methyl2-chloro-5-iodonicotinate 97%
5g
$ 238.00

Crysdot
Methyl2-chloro-5-iodonicotinate 97%
100g
$ 1971.00

Total 28 raw suppliers

Chemical Property of Methyl 2-Chloro-5-iodonicotinate

Chemical Property:

Vapor Pressure:0.000183mmHg at 25°C
Melting Point:70-73°
Boiling Point:329°C at 760 mmHg
Flash Point:152.7°C
PSA：39.19000
Density:1.924g/cm³
LogP:2.12620
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:296.90535
Heavy Atom Count:12
Complexity:179

Purity/Quality:

97% ^*data from raw suppliers

Methyl 2-chloro-5-iodonicotinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(N=CC(=C1)I)Cl

Technology Process of Methyl 2-Chloro-5-iodonicotinate

There total 7 articles about Methyl 2-Chloro-5-iodonicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 116387-40-7
methyl 2-hydroxy-5-iodopyridine-3-carboxylate

: 78686-83-6
methyl 2-chloro-5-iodo-3-pyridinecarboxylate

Guidance literature:: With trichlorophosphate; for 24h; Heating / reflux;

Reference yield: 83.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 59782-86-4
2-chloro-5-iodonicotinic acid

: 78686-83-6
methyl 2-chloro-5-iodo-3-pyridinecarboxylate

Guidance literature:: In diethyl ether; Ambient temperature;
DOI:10.1021/je00025a033

Reference yield: 66.0%

: 116387-40-7
methyl 5-iodo-2-oxo-1,2-dihydro-3-pyridinecarboxylate

: 78686-83-6
methyl 2-chloro-5-iodo-3-pyridinecarboxylate

Guidance literature:: With trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide; for 28h; Ambient temperature;
DOI:10.1021/jo00276a023