6-Hydroxy-2-methylindole

Base Information

• Chemical Name: 6-Hydroxy-2-methylindole
• CAS No.: 54584-22-4
• Molecular Formula: C9H9NO
• Molecular Weight: 147.177
• Hs Code.: 2933990090
• Mol file: 54584-22-4.mol

Synonyms:ZINC16698016;

Chemical Property of 6-Hydroxy-2-methylindole

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.704
• Boiling Point: 344.843 °C at 760 mmHg
• PKA: 10.23±0.40(Predicted)
• Flash Point: 162.355 °C
• PSA: 36.02000
• Density: 1.262 g/cm³
• LogP: 2.18190
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

NLT 98% ^*data from raw suppliers

2-Methyl-1H-indol-6-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Hydroxy-2-methylindole

There total 2 articles about 6-Hydroxy-2-methylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-methyl-6-methoxy-1H-indole (1968-13-4) + aqueous hydrogen bromide + sodium hydrogencarbonate (144-55-8) → 6-hydroxy-2-methyl indole (54584-22-4)

Guidance literature:

In tetrahydrofuran; acetic acid; ethyl acetate;

Reference yield:

→ 6-hydroxy-2-methyl indole (54584-22-4)

Guidance literature:

/BRN= 462499/ (3), Pyrolyse;

Reference yield:

6-hydroxy-2-methyl indole (54584-22-4) + benzyl chloride (100-44-7) → 6-(phenylmethoxy)-2-methylindole (57330-46-8)

Guidance literature:

With potassium carbonate; In ethanol; ethyl acetate; N,N-dimethyl-formamide;

upstream raw materials:

2-methyl-6-methoxy-1H-indole

sodium hydrogencarbonate

Downstream raw materials:

6-(phenylmethoxy)-2-methylindole

Refernces

• 1、 -. "Process for dyeing keratin fibres with a monohydroxyindole associated with an iodide and hydrogen peroxide". . . Retrieved 2008/06/13.