methyl 2,3-(4-phenyl)-1H-2-pyrimidonyl-olean-12-en-28-oate

Base Information

• Chemical Name: methyl 2,3-(4-phenyl)-1H-2-pyrimidonyl-olean-12-en-28-oate
• CAS No.: 1579240-67-7
• Molecular Formula: C₃₉H₅₂N₂O₃
• Molecular Weight: 596.853
• Mol file: 1579240-67-7.mol

Synonyms:methyl 2,3-(4-phenyl)-1H-2-pyrimidonyl-olean-12-en-28-oate

Chemical Property of methyl 2,3-(4-phenyl)-1H-2-pyrimidonyl-olean-12-en-28-oate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,3-(4-phenyl)-1H-2-pyrimidonyl-olean-12-en-28-oate

There total 4 articles about methyl 2,3-(4-phenyl)-1H-2-pyrimidonyl-olean-12-en-28-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

urea (57-13-6) + methyl-3-oxo-2-phenylmethylene-olean-12-ene-28-methyl ester (170240-93-4) → methyl 2,3-(4-phenyl)-1H-2-pyrimidonyl-olean-12-en-28-oate (1579240-67-7)

Guidance literature:

With potassium hydroxide; In ethanol; Reflux;

DOI:10.1016/j.ejmech.2013.12.040

Reference yield:

methyl 3-oxooleanolate (1721-58-0) → methyl 2,3-(4-phenyl)-1H-2-pyrimidonyl-olean-12-en-28-oate (1579240-67-7)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol / 2 h / 20 °C

2: potassium hydroxide / ethanol / Reflux

With potassium hydroxide; In ethanol;

DOI:10.1016/j.ejmech.2013.12.040

Reference yield:

oleanolic acid methyl ester (1724-17-0,73584-64-2) → methyl 2,3-(4-phenyl)-1H-2-pyrimidonyl-olean-12-en-28-oate (1579240-67-7)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridinium chlorochromate / dichloromethane / 2 h / 20 °C

2: potassium hydroxide / ethanol / 2 h / 20 °C

3: potassium hydroxide / ethanol / Reflux

With pyridinium chlorochromate; potassium hydroxide; In ethanol; dichloromethane;

DOI:10.1016/j.ejmech.2013.12.040

upstream raw materials:

oleanolic acid methyl ester

methyl 3-oxooleanolate

urea

methyl-3-oxo-2-phenylmethylene-olean-12-ene-28-methyl ester