N-(3,5-Difluorobenzyl)ethylenediamine

Base Information

Chemical Name:N-(3,5-Difluorobenzyl)ethylenediamine
CAS No.:123566-40-5
Molecular Formula:C₉H₁₂F₂N₂
Molecular Weight:186.204
Hs Code.:
DSSTox Substance ID:DTXSID201230911

Synonyms:N-(3,5-Difluorobenzyl)ethylenediamine;123566-40-5;SCHEMBL10480686;JCCBTSDJBBUQAK-UHFFFAOYSA-N;DTXSID201230911;N1-[(3,5-Difluorophenyl)methyl]-1,2-ethanediamine

Suppliers and Price of N-(3,5-Difluorobenzyl)ethylenediamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(3,5-Difluorobenzyl)ethylenediamine

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:186.09685472
Heavy Atom Count:13
Complexity:134

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C=C(C=C1F)F)CNCCN

Technology Process of N-(3,5-Difluorobenzyl)ethylenediamine

There total 2 articles about N-(3,5-Difluorobenzyl)ethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 32085-88-4
3,5-difluorobenzaldehyde

: 123566-40-5
N-(3,5-difluorobenzyl)ethylenediamine

Guidance literature:: With sodium borohydrid; ethylenediamine; In methanol;

Reference yield:

: 32085-88-4
3,5-difluorobenzaldehyde

: 107-15-3,85404-18-8
ethylenediamine

: 123566-40-5
N-(3,5-difluorobenzyl)ethylenediamine

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 - 20 ℃;
DOI:10.1021/jm00164a051

Reference yield:

: 123566-40-5
N-(3,5-difluorobenzyl)ethylenediamine

: 123566-46-1
1-(3,5-difluorobenzyl)imidazoline-2-thione

Guidance literature:: Multi-step reaction with 2 steps

1: ethyl acetate / 0 °C

2: N-methyl-2-pyrrolidinone / 0.25 h / 185 °C

With 1-methyl-pyrrolidin-2-one; In ethyl acetate;
DOI:10.1021/jm00164a051