4-(Pentyloxy)-4'-biphenylcarboxylic acid

Base Information

• Chemical Name: 4-(Pentyloxy)-4'-biphenylcarboxylic acid
• CAS No.: 59748-15-1
• Molecular Formula: C18H20O3
• Molecular Weight: 284.355
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID60551422
• Nikkaji Number: J1.118.856G
• Wikidata: Q82431078
• Mol file: 59748-15-1.mol

Synonyms:59748-15-1;4-(Pentyloxy)-4'-biphenylcarboxylic acid;4-(4-pentoxyphenyl)benzoic acid;4'-(PENTYLOXY)-[1,1'-BIPHENYL]-4-CARBOXYLIC ACID;4-n-Pentyloxybiphenyl-4'-carboxylic acid;4'-PENTYLOXYBIPHENYL-4-CARBOXYLIC ACID;SCHEMBL2490183;DTXSID60551422;MFCD00799361;AKOS004116829;4'-(pentyloxy)biphenyl-4-carboxylic acid;4-(pentyloxy)biphenyl-4'-carboxylic acid;BS-52258;CS-0152125;A832450;4'-(Pentyloxy)[1,1'-biphenyl]-4-carboxylic acid;4'-(PENTYLOXY)-[1,1'-BIPHENYL]-4-CARBOXYLICACID

Chemical Property of 4-(Pentyloxy)-4'-biphenylcarboxylic acid

Chemical Property:

• PSA: 46.53000
• LogP: 4.62080
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 284.14124450
• Heavy Atom Count: 21
• Complexity: 300

Purity/Quality:

98%min ^*data from raw suppliers

4'-(Pentyloxy)-[1,1'-biphenyl]-4-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCOC1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)O

Technology Process of 4-(Pentyloxy)-4'-biphenylcarboxylic acid

There total 11 articles about 4-(Pentyloxy)-4'-biphenylcarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

4'-pentyloxy-4-methylbiphenyl (245056-76-2) → 4'-n-pentyloxybiphenyl-4-carboxylic acid (59748-15-1)

Guidance literature:

With sodium bromide; zirconium oxide; manganese; cobalt; In acetic anhydride; acetic acid; at 105 ℃;

Reference yield: 76.6%

1-Bromopentane (110-53-2) + 4'-Hydroxybiphenyl-4-carboxylic acid (58574-03-1) → 4'-n-pentyloxybiphenyl-4-carboxylic acid (59748-15-1)

Guidance literature:

1-Bromopentane; 4'-Hydroxybiphenyl-4-carboxylic acid; With potassium hydroxide; In ethanol; water; for 24h; Inert atmosphere; Reflux;

With hydrogenchloride; In ethanol; water; pH=6;

DOI:10.1016/j.tet.2012.02.015

Reference yield: 76.0%

4'-(pentyloxy)-4-biphenylcarbonitrile (52364-71-3) → 4'-n-pentyloxybiphenyl-4-carboxylic acid (59748-15-1)

Guidance literature:

With potassium hydroxide; In methanol; water; for 120h; Heating;

DOI:10.1080/00268948108073618

upstream raw materials:

4'-(pentyloxy)-4-biphenylcarbonitrile

4'-pentyloxy-4-methylbiphenyl

4'-Hydroxybiphenyl-4-carboxylic acid

amyl iodide

Downstream raw materials:

tert-butyl 4-<(2R)-2-cyano-7-<4-<<<4'-(pentyloxy)-4-biphenyl>carbonyl>oxy>phenyl>heptylidene>benzoate

4-ferrocenylphenyl-4'-pentyloxy-4-biphenylcarboxylate

cyclo-[Orn(Nα-4'-pentyloxy-biphenyl-4-formyl)-Ser-Pro-hTyr-Orn(Nδ-Cbz)-Pro(4S-N3)]

cyclo-[Orn(Nα-4'-pentyloxy-biphenyl-4-formyl)-Thr-Pro-hTyr-Lys(Nε-Cbz)-Pro(4S-N3)]