Cyclobutanecarboxylic acid, 2,2-dimethyl-3-oxo-, methyl ester, (1S)-(9CI)

Base Information

Chemical Name:Cyclobutanecarboxylic acid, 2,2-dimethyl-3-oxo-, methyl ester, (1S)-(9CI)
CAS No.:527751-17-3
Molecular Formula:C8H12O3
Molecular Weight:156.17908
Hs Code.:
DSSTox Substance ID:DTXSID501219908
Nikkaji Number:J1.865.441E
Mol file:527751-17-3.mol

Synonyms:527751-17-3;Cyclobutanecarboxylic acid, 2,2-dimethyl-3-oxo-, methyl ester, (1S)- (9CI);DTXSID501219908;Cyclobutanecarboxylic acid, 2,2-dimethyl-3-oxo-, methyl ester, (1S)-;Methyl (1S)-2,2-dimethyl-3-oxocyclobutanecarboxylate;METHYL (1S)-2,2-DIMETHYL-3-OXOCYCLOBUTANE-1-CARBOXYLATE

Suppliers and Price of Cyclobutanecarboxylic acid, 2,2-dimethyl-3-oxo-, methyl ester, (1S)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Cyclobutanecarboxylic acid, 2,2-dimethyl-3-oxo-, methyl ester, (1S)-(9CI)

Chemical Property:

Boiling Point:201.5±33.0 °C(Predicted)
PSA：0.00000
Density:1.088±0.06 g/cm3(Predicted)
LogP:0.00000
XLogP3:0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:156.078644241
Heavy Atom Count:11
Complexity:205

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(C(CC1=O)C(=O)OC)C
Isomeric SMILES:CC1([C@H](CC1=O)C(=O)OC)C

Technology Process of Cyclobutanecarboxylic acid, 2,2-dimethyl-3-oxo-, methyl ester, (1S)-(9CI)

There total 10 articles about Cyclobutanecarboxylic acid, 2,2-dimethyl-3-oxo-, methyl ester, (1S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1392804-41-9,1392804-27-1,1392804-78-2
(1S,3R)-methyl 3-hydroxy-2,2-dimethylcyclobutanecarboxylate

: 527751-17-3
(1S)-methyl 2,2-dimethyl-3-oxocyclobutanecarboxylate

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1080/00397911.2014.898308

Reference yield: 66.0%

: 26189-59-3
1-chloro-1-(dimethylamino)-2-methyl-1-propene

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 78685-51-5,527751-17-3
2,2-dimethyl-3-oxo-cyclobutanecarboxylic acid methyl ester

Guidance literature:: 1-chloro-1-(dimethylamino)-2-methyl-1-propene; acrylic acid methyl ester; With zinc trifluoromethanesulfonate; at 35 ℃; for 6h; Neat (no solvent); Microwave irradiation;

With water; In tetrahydrofuran; for 1h;
DOI:10.1021/jo102257k