Methyl 5-(2-aminophenyl)furan-2-carboxylate

Base Information

Chemical Name:Methyl 5-(2-aminophenyl)furan-2-carboxylate
CAS No.:54023-14-2
Molecular Formula:C12H11NO3
Molecular Weight:217.224
Hs Code.:2932190090
European Community (EC) Number:675-476-1
DSSTox Substance ID:DTXSID20409339
Wikidata:Q82215134
Mol file:54023-14-2.mol

Synonyms:methyl 5-(2-aminophenyl)furan-2-carboxylate;54023-14-2;methyl 5-(2-aminophenyl)-2-furoate;5-(2-Amino-phenyl)-furan-2-carboxylic acid methyl ester;5-(2-aminophenyl)furan-2-carboxylic acid methyl ester;2-Furancarboxylic acid, 5-(2-aminophenyl)-, methyl ester;SCHEMBL4937140;DTXSID20409339;VFWZTMZWNJSVMH-UHFFFAOYSA-N;AKOS005207133;SB61547;CS-0331831;FT-0736207

Suppliers and Price of Methyl 5-(2-aminophenyl)furan-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

CHESS?
AN051024:5-(2-Amino-phenyl)-furan-2-carboxylicacidmethylester 97
5 g
$ 1020.00

American Custom Chemicals Corporation
5-(2-AMINOPHENYL)FURAN-2-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 500.13

Total 5 raw suppliers

Chemical Property of Methyl 5-(2-aminophenyl)furan-2-carboxylate

Chemical Property:

PSA：65.46000
LogP:2.89660
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:217.07389321
Heavy Atom Count:16
Complexity:257

Purity/Quality:

99% ^*data from raw suppliers

AN051024:5-(2-Amino-phenyl)-furan-2-carboxylicacidmethylester 97 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC=C(O1)C2=CC=CC=C2N

Technology Process of Methyl 5-(2-aminophenyl)furan-2-carboxylate

There total 3 articles about Methyl 5-(2-aminophenyl)furan-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 41019-36-7
5-(2-nitrophenyl)furan-2-carboxylic acid methyl ester

: 54023-14-2
5-(2-aminophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 2h; under 2280 Torr;
DOI:10.1021/jm0492305

Reference yield:

: 2527-99-3
methyl 5-bromo-2-furoate

: 54023-14-2
5-(2-aminophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / Pd(PPh₃)4; aq. Na₂CO₃ / toluene; methanol / 6 h / Heating

2: 94 percent / H₂ / Pd/C / methanol / 2 h / 20 °C / 2280 Torr

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen; sodium carbonate; palladium on activated charcoal; In methanol; toluene; 1: Suzuki reaction;
DOI:10.1021/jm0492305

Reference yield:

: 5570-19-4
2-nitrophenylboronic acid

: 54023-14-2
5-(2-aminophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / Pd(PPh₃)4; aq. Na₂CO₃ / toluene; methanol / 6 h / Heating

2: 94 percent / H₂ / Pd/C / methanol / 2 h / 20 °C / 2280 Torr

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen; sodium carbonate; palladium on activated charcoal; In methanol; toluene; 1: Suzuki reaction;
DOI:10.1021/jm0492305