1-(1-NAPHTHYL)ETHANOL

Base Information

• Chemical Name: 1-(1-NAPHTHYL)ETHANOL
• CAS No.: 57605-95-5
• Molecular Formula: C12H12O
• Molecular Weight: 172.227
• Mol file: 57605-95-5.mol

Synonyms:ALPHA-METHYL-1-NAPHTHALENEMETHANOL;ALPHA-NAPHTHYL METHYL CARBINOL;A-NAPHTHYLMETHYLCARBINOL;1-(1-HYDROXYETHYL)NAPHTHALENE;(+/-)-1-(1-NAPHTHYL)ETHANOL;1-(1-NAPHTHYL)ETHANOL;AURORA KA-6960;(+ -)-1-(1-NAPHTHYL)ETHANOL 99%

Chemical Property of 1-(1-NAPHTHYL)ETHANOL

Chemical Property:

• Melting Point: 63-65 °C
• Refractive Index: 1.6188 (estimate)
• Boiling Point: 262.55°C (rough estimate)
• PSA: 20.23000
• Density: 1.1190
• LogP: 2.89310

Purity/Quality:

97% ^*data from raw suppliers

(+/-)-1-(1-Naphthyl)ethanol 98% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(1-NAPHTHYL)ETHANOL

There total 56 articles about 1-(1-NAPHTHYL)ETHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1'-naphthacetophenone (941-98-0) → 1-(1-naphthyl)ethanol (57605-95-5,1517-72-2)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 2h;

DOI:10.1021/ol048993j

Reference yield: 97.0%

methyl magnesium iodide (917-64-6) + 1-naphthaldehyde (66-77-3) → 1-(1-naphthyl)ethanol (57605-95-5,1517-72-2)

Guidance literature:

In diethyl ether; for 2h; Ambient temperature;

DOI:10.1021/jm00082a017

Reference yield: 90.0%

1-acetonaphthone → 1-(1-naphthyl)ethanol (57605-95-5,1517-72-2)

Guidance literature:

With methanol; sodium tetrahydroborate; nickel(II) chloride hexahydrate; at 20 ℃; for 1h;

DOI:10.1007/s00706-015-1608-3

upstream raw materials:

1'-naphthacetophenone

diethyl ether

acetaldehyde

1-naphthylmagnesiumbromide

Downstream raw materials:

1'-naphthacetophenone

1-vinylnaphthalene

(S)-1-(1-Naphthyl)ethanol

(R)-1-(naphth-1-yl)ethanol

Refernces

• 1、 Oestreich, Martin,Seliger, Jan. "Dynamic Kinetic Resolution of Alcohols by Enantioselective Silylation Enabled by Two Orthogonal Transition-Metal Catalysts". supporting information. p. 247 - 251. Retrieved 2020/10/29.
• 2、 Tsaulwayo, Nokwanda,Kumah, Robert T.,Ojwach, Stephen O.. "Synthesis and structural elucidation of (pyridyl)imine Fe(II) complexes and their applications as catalysts in transfer hydrogenation of ketones". . . Retrieved 2021/01/25.