1-(2-Aminophenyl)-2-chloroethanone

Base Information

Chemical Name:1-(2-Aminophenyl)-2-chloroethanone
CAS No.:64605-23-8
Molecular Formula:C8H8ClNO
Molecular Weight:169.611
Hs Code.:2922399090
DSSTox Substance ID:DTXSID00497491
Wikidata:Q82347081
Mol file:64605-23-8.mol

Synonyms:64605-23-8;1-(2-aminophenyl)-2-chloroethanone;Ethanone, 1-(2-aminophenyl)-2-chloro;1-(2-Aminophenyl)-2-chloroethan-1-one;2'-amino-2-chloroacetophenone;2-aminophenacyl chloride;SCHEMBL4233746;DTXSID00497491;HWIRWNKBVWOIGM-UHFFFAOYSA-N;AKOS006385694;FT-0649814;A834825

Suppliers and Price of 1-(2-Aminophenyl)-2-chloroethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2-Aminophenyl)-2-chloroethanone 95+%
5g
$ 1841.00

Crysdot
1-(2-Aminophenyl)-2-chloroethanone 95+%
1g
$ 612.00

American Custom Chemicals Corporation
ETHANONE, 1-(2-AMINOPHENYL)-2-CHLORO 95.00%
5G
$ 909.56

AK Scientific
Ethanone,1-(2-aminophenyl)-2-chloro
1g
$ 1531.00

Total 8 raw suppliers

Chemical Property of 1-(2-Aminophenyl)-2-chloroethanone

Chemical Property:

Vapor Pressure:0.00115mmHg at 25°C
Melting Point:112-113 °C
Refractive Index:1.588
Boiling Point:300.1 °C at 760 mmHg
PKA:-0.30±0.10(Predicted)
Flash Point:135.3 °C
PSA：43.09000
Density:1.259 g/cm³
LogP:2.27150
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:169.0294416
Heavy Atom Count:11
Complexity:149

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Aminophenyl)-2-chloroethanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)CCl)N

Technology Process of 1-(2-Aminophenyl)-2-chloroethanone

There total 7 articles about 1-(2-Aminophenyl)-2-chloroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 142-04-1,36663-09-9
aniline hydrochloride

: 107-14-2
chloroacetonitrile

: 64605-23-8
2'-amino-2-chloroacetophenone

Guidance literature:: aniline hydrochloride; With boron trichloride; In dichloromethane; 1,2-dichloro-ethane; at 20 ℃; for 0.5h;

chloroacetonitrile; With zinc(II) chloride; In dichloromethane; 1,2-dichloro-ethane; at 75 ℃; for 24h;

With hydrogenchloride; In water; at 75 ℃; for 30h;
DOI:10.1002/jlcr.1067

Reference yield: 72.0%

: 107-14-2
chloroacetonitrile

: 62-53-3
aniline

: 64605-23-8
2'-amino-2-chloroacetophenone

Guidance literature:: aniline; With boron trichloride; In 1,2-dichloro-ethane;

chloroacetonitrile; With zinc(II) chloride; In 1,2-dichloro-ethane; for 24h; Reflux; Inert atmosphere;

With hydrogenchloride; water; In 1,2-dichloro-ethane; for 1h; Reflux;
DOI:10.1002/cmdc.201600327