(R)-2-Isobutyl-succinic acid 4-tert-butyl ester 1-pentafluorophenyl ester

Base Information

Chemical Name:(R)-2-Isobutyl-succinic acid 4-tert-butyl ester 1-pentafluorophenyl ester
CAS No.:144287-84-3
Molecular Formula:C₁₈H₂₁F₅O₄
Molecular Weight:396.354
Hs Code.:

Synonyms:(R)-2-Isobutyl-succinic acid 4-tert-butyl ester 1-pentafluorophenyl ester

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Chemical Property of (R)-2-Isobutyl-succinic acid 4-tert-butyl ester 1-pentafluorophenyl ester

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Technology Process of (R)-2-Isobutyl-succinic acid 4-tert-butyl ester 1-pentafluorophenyl ester

There total 1 articles about (R)-2-Isobutyl-succinic acid 4-tert-butyl ester 1-pentafluorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 771-61-9
2,3,4,5,6-pentafluorophenol

: 112245-04-2
(R)-2-(2-(tert-butoxy)-2-oxoethyl)-4-methylpentanoic acid

: 144287-84-3
(R)-2-Isobutyl-succinic acid 4-tert-butyl ester 1-pentafluorophenyl ester

Guidance literature:: With dicyclohexyl-carbodiimide; In ethyl acetate; at 0 - 20 ℃;
DOI:10.1021/jo0110698

Reference yield: 84.0%

: 144287-84-3
(R)-2-Isobutyl-succinic acid 4-tert-butyl ester 1-pentafluorophenyl ester

: 443149-83-5
[1S-(1α,2β,3β)]-(2-(4-methoxyphenyl)-3-triisopropylsilyloxymethyl)cyclopropane-1N-allyloxycarbonylaminocyclopropane

: 443149-84-6
[1S-(1β,2α,3α)]-1-[(2-(R)-isobutyl-4-tert-butoxycarboxyl)butanoyl]amino-3-(4-methoxyphenyl)-2-triisopropylsilyloxymethylcyclopropane

Guidance literature:: With tri-n-butyl-tin hydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In dichloromethane; Heating;
DOI:10.1021/jo0110698

Reference yield:

: 144287-84-3
(R)-2-Isobutyl-succinic acid 4-tert-butyl ester 1-pentafluorophenyl ester

: 210710-86-4
(R)-3-[(S)-1-Benzyl-2-(1H-indol-3-yl)-2-oxo-ethylcarbamoyl]-5-methyl-hexanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / 45 °C

2: TFA

With trifluoroacetic acid; In N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(98)00597-6