Cyano-1-(formylamido)-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester

Base Information

Chemical Name:Cyano-1-(formylamido)-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester
CAS No.:290812-77-0
Molecular Formula:C₁₇H₂₅N₂O₄P
Molecular Weight:352.37
Hs Code.:

Synonyms:Cyano-1-(formylamido)-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester

Suppliers and Price of Cyano-1-(formylamido)-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Cyano-1-(formylamido)-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Cyano-1-(formylamido)-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester

There total 4 articles about Cyano-1-(formylamido)-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 2258-42-6
formyl acetic anhydride

: 290812-68-9
1-Amino-1-cyano-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester

: 290812-77-0
Cyano-1-(formylamido)-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester

Guidance literature:: In dichloromethane; at -78 - 20 ℃; for 15h;
DOI:10.1055/s-2000-6315

Reference yield:

: 4484-74-6
4-methylbenzyl iodide

: 290812-77-0
Cyano-1-(formylamido)-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / 1,2-dimethoxy-ethane / 0.75 h / -10 °C

1.2: 81 percent / 1,2-dimethoxy-ethane / 17.5 h / -10 - 20 °C

2.1: NaH / toluene / 0.25 h / -78 °C

2.2: 25 percent / NH₂Cl / toluene; diethyl ether / 19 h / -78 - 20 °C

3.1: 70 percent / CH₂Cl₂ / 15 h / -78 - 20 °C

With sodium hydride; In 1,2-dimethoxyethane; dichloromethane; toluene; 1.1: Metallation / 1.2: Alkylation / 2.1: Metallation / 2.2: Amination / 3.1: Formylation;
DOI:10.1055/s-2000-6315

Reference yield:

: 21658-95-7
diisopropyl (cyanomethyl)phosphonate

: 290812-77-0
Cyano-1-(formylamido)-2-(4-methylphenyl)ethylphosphonsaeurediisopropylester

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / 1,2-dimethoxy-ethane / 0.75 h / -10 °C

1.2: 81 percent / 1,2-dimethoxy-ethane / 17.5 h / -10 - 20 °C

2.1: NaH / toluene / 0.25 h / -78 °C

2.2: 25 percent / NH₂Cl / toluene; diethyl ether / 19 h / -78 - 20 °C

3.1: 70 percent / CH₂Cl₂ / 15 h / -78 - 20 °C

With sodium hydride; In 1,2-dimethoxyethane; dichloromethane; toluene; 1.1: Metallation / 1.2: Alkylation / 2.1: Metallation / 2.2: Amination / 3.1: Formylation;
DOI:10.1055/s-2000-6315