N⁵-Benzoyl-5-amino-1-(phenylsulfonyl)indole

Base Information

Chemical Name:N⁵-Benzoyl-5-amino-1-(phenylsulfonyl)indole
CAS No.:124400-50-6
Molecular Formula:C₂₁H₁₆N₂O₃S
Molecular Weight:376.436
Hs Code.:

N<sup>5</sup>-Benzoyl-5-amino-1-(phenylsulfonyl)indole

Synonyms:N⁵-Benzoyl-5-amino-1-(phenylsulfonyl)indole

Suppliers and Price of N⁵-Benzoyl-5-amino-1-(phenylsulfonyl)indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N⁵-Benzoyl-5-amino-1-(phenylsulfonyl)indole

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N⁵-Benzoyl-5-amino-1-(phenylsulfonyl)indole

There total 9 articles about N⁵-Benzoyl-5-amino-1-(phenylsulfonyl)indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 124400-52-8
1-Benzenesulfonyl-1H-indol-5-yl amine

: 98-88-4
benzoyl chloride

: 124400-50-6
N⁵-Benzoyl-5-amino-1-(phenylsulfonyl)indole

Guidance literature:: With potassium carbonate; In tetrahydrofuran; at 25 ℃; for 6h;
DOI:10.1021/jo00291a059

Reference yield:

: 3393-96-2
p-nitrobenzanilide

: 124400-50-6
N⁵-Benzoyl-5-amino-1-(phenylsulfonyl)indole

Guidance literature:: Multi-step reaction with 5 steps

1: 99 percent / H₂ / 10percent Pd/C / ethyl acetate / 2 h / 25 °C / 2585.7 Torr

2: 84 percent / pyridine / tetrahydrofuran / 8 h / Heating

3: 79 percent / lead tetraacetate / CHCl₃ / 12 h / 25 °C

4: 67 percent / BF₃*Et₂O / CH₂Cl₂ / 24 h / -20 °C

5: 1) OsO₄, NaIO₄, 2) H₂SO₄ (5percent in CH₂Cl₂) / 1) acetone, water, 25 deg C, 2 h, 2) CH₂Cl₂, 25 deg C, 8 h

With pyridine; lead(IV) acetate; sodium periodate; osmium(VIII) oxide; sulfuric acid; boron trifluoride diethyl etherate; hydrogen; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; chloroform; ethyl acetate;
DOI:10.1021/jo00291a059

Reference yield:

: 124400-51-7
5-nitro-1-(phenylsulfonyl)-1H-indole

: 124400-50-6
N⁵-Benzoyl-5-amino-1-(phenylsulfonyl)indole

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / H₂ / 10percent Pd/C / tetrahydrofuran / 2 h / 25 °C / 760 Torr

2: 85 percent / K₂CO₃ / tetrahydrofuran / 6 h / 25 °C

With hydrogen; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran;
DOI:10.1021/jo00291a059