3393-96-2

Basic information

• Product Name: 4'-NITROBENZANILIDE
• Synonyms: N-(4-NITROPHENYL)BENZAMIDE;4'-NITROBENZANILIDE;4''-NITROBENZANILIDE 97+%;Aniline, N-benzoyl-p-nitro-;Benzamide, N-(4-nitrophenyl)-;Benzamide, N-(p-nitrophenyl)-;Benzamide,N-(4-nitrophenyl)-;Benzanilide, 4'-nitro-
• CAS NO: 3393-96-2
• Molecular Formula: C₁₃H₁₀N₂O₃
• Molecular Weight: 242.23
• EINECS: 222-241-2
• Mol File: 3393-96-2.mol
• Article Data: 205

Chemical Properties

• Melting Point: 202-204°C
• Boiling Point: 327°Cat760mmHg
• Flash Point: 151.5°C
• Appearance: /
• Density: 1.344g/cm³
• Vapor Pressure: 0.000209mmHg at 25°C
• Refractive Index: 1.671
• CAS DataBase Reference: 4'-NITROBENZANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-NITROBENZANILIDE(3393-96-2)
• EPA Substance Registry System: 4'-NITROBENZANILIDE(3393-96-2)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 3393-96-2(Hazardous Substances Data)

Usage

General Description

4'-Nitrobenzanilide is a chemical compound distinguished by its systematic name N-Phenyl-4-nitrobenzamide. This organic compound consists of a benzene ring attached to an anilide group and a nitro group, making it a derivative of aniline and a form of secondary aromatic amine. It is based on a general structure where the parent is benzanilide. The chemical is often used in research and development processes, especially in the generation of other complex compounds. The compound exhibits a melting point of between 188-191°C. However, it should be handled with caution due to its potential for causing eye and skin irritation.

InChI:InChI=1/C13H10N2O3/c16-13(10-4-2-1-3-5-10)14-11-6-8-12(9-7-11)15(17)18/h1-9H,(H,14,16)

Upstream product

• 64-19-7 acetic acid 
• 4702-72-1 benzil mono(p-nitrophenylhydrazone) 
• 100-01-6 4-nitro-aniline 
• 93-97-0 benzoic acid anhydride 
• 38430-05-6 (E)-N-phenylbenzimidoyl chloride 
• 18039-42-4 5-Phenyl-1H-tetrazole 
• 98-88-4 benzoyl chloride 
• 613-94-5 benzoic acid hydrazide 
• 93-98-1 N-phenyl benzoyl amide 
• 7697-37-2 nitric acid 
• 5265-19-0 N-(4-nitrophenyl)thiobenzamide 
• 2797-52-6 mono-O-benzoyl maleic hydrazide 
• 848417-68-5 3,6-dibenzoyloxy-1,2-pyridazine 
• 613-90-1 benzoyl cyanide 

Downstream Products

• 55-21-0 benzamide 
• 100-01-6 4-nitro-aniline 
• 100990-64-5 N-benzoyl-2-(N-benzoyl)amino-5,4'-dinitrodiphenylamine 
• 1775-95-7 2-amino-5-nitrobenzophenone 
• 65-85-0 benzoic acid 
• 100-52-7 benzaldehyde 
• 3646-57-9 bis(4-nitrophenyl)diazene 
• 53288-66-7 N-(4-nitrophenyl)-N'-phenylcarbodiimide 
• 57761-71-4 1-(4-nitrophenyl)-5-phenyltetrazole 
• 1045325-34-5 C₁₄H₁₃N₅O₂S 
• 73333-79-6 N-(4-nitrophenyl)-N-phenylbenzamide 
• 124400-42-6 N⁴-Benzoyl-N¹-(phenylsulfonyl)-1,4-diamino-3-(1,1-bis(methoxycarbonyl)methyl)benzene 
• 124400-43-7 N⁴-Benzoyl-N¹-(phenylsulfonyl)-1,4-diamino-3-(1-(methoxycarbonyl)-2-oxopropyl)benzene 
• 124400-44-8 N⁴-Benzoyl-N¹-(phenylsulfonyl)-1,4-diamino-3-morpholylbenzene 

Relevant articles and documents

Use of halomethyl resins to immobilize amines: An efficient method for synthesis of sulfonamides and amides on a solid support

Methods for the synthesis of chloromethyl and bromomethyl equivalents of Wang's resin are described. To explore the utility of this acid clearable resin, amines were immobilized through the nitrogen atom, further functionalized, and then cleaved under acid conditions.

Carboxylic Acid Deoxyfluorination and One-Pot Amide Bond Formation Using Pentafluoropyridine (PFP)

This work describes the application of pentafluoropyridine (PFP), a cheap commercially available reagent, in the deoxyfluorination of carboxylic acids to acyl fluorides. The acyl fluorides can be formed from a range of acids under mild conditions. We also demonstrate that PFP can be utilized in a one-pot amide bond formation via in situ generation of acyl fluorides. This one-pot deoxyfluorination amide bond-forming reaction gives ready access to amides in yields of ≤94%.

N,O-Benzyl Protection of Structurally Varied Amines and Phenols Using Wells-Dawson Heteropolyacid Catalyst

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