2,2-Dimethyl-propionic acid (1S,2R,5R)-5-isopropenyl-2-methyl-cyclohexyl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid (1S,2R,5R)-5-isopropenyl-2-methyl-cyclohexyl ester
CAS No.:218268-99-6
Molecular Formula:C₁₅H₂₆O₂
Molecular Weight:238.37
Hs Code.:

Synonyms:2,2-Dimethyl-propionic acid (1S,2R,5R)-5-isopropenyl-2-methyl-cyclohexyl ester

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Chemical Property of 2,2-Dimethyl-propionic acid (1S,2R,5R)-5-isopropenyl-2-methyl-cyclohexyl ester

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Technology Process of 2,2-Dimethyl-propionic acid (1S,2R,5R)-5-isopropenyl-2-methyl-cyclohexyl ester

There total 2 articles about 2,2-Dimethyl-propionic acid (1S,2R,5R)-5-isopropenyl-2-methyl-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 20549-48-8,17699-09-1
(+)-neodihydrocarveol

: 3282-30-2
pivaloyl chloride

: 218268-99-6
2,2-Dimethyl-propionic acid (1S,2R,5R)-5-isopropenyl-2-methyl-cyclohexyl ester

Guidance literature:: With triethylamine; In dichloromethane;
DOI:10.1016/S0040-4039(98)01784-5

Reference yield:

: 5524-05-0
(2R,5R)-5-isopropenyl-2-methylcyclohexanone

: 218268-99-6
2,2-Dimethyl-propionic acid (1S,2R,5R)-5-isopropenyl-2-methyl-cyclohexyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / Li(s-Bu)3BH

2: 67 percent / NEt₃ / CH₂Cl₂

With L-Selectride; triethylamine; In dichloromethane;
DOI:10.1016/S0040-4039(98)01784-5

Reference yield:

: 218268-99-6
2,2-Dimethyl-propionic acid (1S,2R,5R)-5-isopropenyl-2-methyl-cyclohexyl ester

: 218269-01-3
2,2-Dimethyl-propionic acid (1S,2R,5R)-5-hydroxy-2-methyl-cyclohexyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) O₃; 2.) DMAP / 1.) MeOH/CH₂Cl₂

2: NaOH / methanol

With dmap; sodium hydroxide; ozone; In methanol;
DOI:10.1016/S0040-4039(98)01784-5