3,4-dimethoxy-β-methylthio-β-(p-tolylsulfonyl)styrene

Base Information

• Chemical Name: 3,4-dimethoxy-β-methylthio-β-(p-tolylsulfonyl)styrene
• CAS No.: 87228-74-8
• Molecular Formula: C₁₈H₂₀O₄S₂
• Molecular Weight: 364.486
• Mol file: 87228-74-8.mol

Synonyms:3,4-dimethoxy-β-methylthio-β-(p-tolylsulfonyl)styrene

Chemical Property of 3,4-dimethoxy-β-methylthio-β-(p-tolylsulfonyl)styrene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-dimethoxy-β-methylthio-β-(p-tolylsulfonyl)styrene

There total 2 articles about 3,4-dimethoxy-β-methylthio-β-(p-tolylsulfonyl)styrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

methylthiomethyl p-tolyl sulfone (59662-65-6) + 3,4-dimethoxy-benzaldehyde (120-14-9) → 3,4-dimethoxy-β-methylthio-β-(p-tolylsulfonyl)styrene (87228-74-8)

Guidance literature:

With potassium carbonate; In isopropyl alcohol; Heating;

DOI:10.1246/cl.1986.1597

Reference yield:

sodium 4-methylbenzenesulfinate (824-79-3) → 3,4-dimethoxy-β-methylthio-β-(p-tolylsulfonyl)styrene (87228-74-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) acetic anhydride; 2.) acetic acid, sodium acetate / 1.) 80 deg C, 24 h; 2.) 100 deg C, 26 h

2: 68 percent / K₂CO₃ / propan-2-ol / 45 h / Heating

With sodium acetate; acetic anhydride; potassium carbonate; acetic acid; In isopropyl alcohol;

DOI:10.1246/cl.1983.767

Reference yield: 90.0%

3,4-dimethoxy-β-methylthio-β-(p-tolylsulfonyl)styrene (87228-74-8) → 1,2-Dimethoxy-4-[2-methylsulfanyl-2-(toluene-4-sulfonyl)-ethyl]-benzene (107951-77-9)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 6h; Ambient temperature;

DOI:10.1246/cl.1986.1597

upstream raw materials:

methylthiomethyl p-tolyl sulfone

3,4-dimethoxy-benzaldehyde

sodium 4-methylbenzenesulfinate

Downstream raw materials:

3,4-dimethoxy-β-methylsulfinyl-β-(p-tolylsulfonyl)styrene

1,2-Dimethoxy-4-[2-methylsulfanyl-2-(toluene-4-sulfonyl)-ethyl]-benzene

3,4-dimethoxyphenylacetone

α-(3,4-dimethoxyphenyl)-α-methoxyacetate