Technology Process of (5Z,25Z)-17-benzenesulfonyl-5,25-hentriacontadiene
There total 7 articles about (5Z,25Z)-17-benzenesulfonyl-5,25-hentriacontadiene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(Z)-15-benzenesulfonyl-6-pentadecene;
With
n-butyllithium;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane;
at -78 ℃;
for 0.0166667h;
(Z)-11-Hexadecenyl bromide;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane;
at -78 - 20 ℃;
Further stages.;
DOI:10.1271/bbb.69.1620
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 94 percent / potassium hexamethyldisilazide / tetrahydrofuran; toluene; hexamethylphosphoric acid triamide / -78 - 20 °C
2.1: butyllithium / hexane; tetrahydrofuran; hexamethylphosphoric acid triamide / 0.02 h / -78 °C
2.2: 70 percent / hexane; tetrahydrofuran; hexamethylphosphoric acid triamide / -78 - 20 °C
With
n-butyllithium; potassium hexamethylsilazane;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; toluene;
1.1: Wittig olefination;
DOI:10.1271/bbb.69.1620
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 96 percent / triphenylphosphine; bromine; pyridine / CH2Cl2 / -30 - 20 °C
2.1: butyllithium / hexane; tetrahydrofuran; hexamethylphosphoric acid triamide / 0.02 h / -78 °C
2.2: 70 percent / hexane; tetrahydrofuran; hexamethylphosphoric acid triamide / -78 - 20 °C
With
pyridine; n-butyllithium; bromine; triphenylphosphine;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; dichloromethane;
DOI:10.1271/bbb.69.1620
