(2-(pyrrolidin-1-yl)phenyl)[2-chloro-4-(E-((morpholin-1-yl)carbonyl)ethenyl)phenyl]sulfide

Base Information

• Chemical Name: (2-(pyrrolidin-1-yl)phenyl)[2-chloro-4-(E-((morpholin-1-yl)carbonyl)ethenyl)phenyl]sulfide
• CAS No.: 280749-36-2
• Molecular Formula: C₂₃H₂₅ClN₂O₂S
• Molecular Weight: 428.983
• Mol file: 280749-36-2.mol

Synonyms:(2-(pyrrolidin-1-yl)phenyl)[2-chloro-4-(E-((morpholin-1-yl)carbonyl)ethenyl)phenyl]sulfide

Chemical Property of (2-(pyrrolidin-1-yl)phenyl)[2-chloro-4-(E-((morpholin-1-yl)carbonyl)ethenyl)phenyl]sulfide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (2-(pyrrolidin-1-yl)phenyl)[2-chloro-4-(E-((morpholin-1-yl)carbonyl)ethenyl)phenyl]sulfide

There total 2 articles about (2-(pyrrolidin-1-yl)phenyl)[2-chloro-4-(E-((morpholin-1-yl)carbonyl)ethenyl)phenyl]sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

pyrrolidine (123-75-1) + 2-bromophenyl-2-chloro-4-((E)-((1-morpholino)carbonyl)ethenyl)phenyl sulfide (280748-79-0) → (2-(pyrrolidin-1-yl)phenyl)[2-chloro-4-(E-((morpholin-1-yl)carbonyl)ethenyl)phenyl]sulfide (280749-36-2)

Guidance literature:

With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 90 ℃; for 2h;

Reference yield: 55.0%

sodium t-butanolate (865-48-5) + 2-bromophenyl-2-chloro-4-((E)-((1-morpholino)carbonyl)ethenyl)phenyl sulfide (280748-79-0) → (2-(pyrrolidin-1-yl)phenyl)[2-chloro-4-(E-((morpholin-1-yl)carbonyl)ethenyl)phenyl]sulfide (280749-36-2)

Guidance literature:

tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In pyrrolidine; toluene;

upstream raw materials:

sodium t-butanolate

2-bromophenyl-2-chloro-4-((E)-((1-morpholino)carbonyl)ethenyl)phenyl sulfide

pyrrolidine