2-[3,5-bis(trifluoromethyl)phenylsulfonyl]-N-methoxy-N-methylacetamide

Base Information

Chemical Name:2-[3,5-bis(trifluoromethyl)phenylsulfonyl]-N-methoxy-N-methylacetamide
CAS No.:1048364-46-0
Molecular Formula:C₁₂H₁₁F₆NO₄S
Molecular Weight:379.28
Hs Code.:

Synonyms:2-[3,5-bis(trifluoromethyl)phenylsulfonyl]-N-methoxy-N-methylacetamide

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Chemical Property of 2-[3,5-bis(trifluoromethyl)phenylsulfonyl]-N-methoxy-N-methylacetamide

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Technology Process of 2-[3,5-bis(trifluoromethyl)phenylsulfonyl]-N-methoxy-N-methylacetamide

There total 1 articles about 2-[3,5-bis(trifluoromethyl)phenylsulfonyl]-N-methoxy-N-methylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1048364-44-8
2-[3,5-bis(trifluoromethyl)phenylsulfanyl]-N-methoxy-N-methylacetamide

: 1048364-46-0
2-[3,5-bis(trifluoromethyl)phenylsulfonyl]-N-methoxy-N-methylacetamide

Guidance literature:: With manganese (II) sulfate monohydrate; dihydrogen peroxide; sodium hydrogencarbonate; In water; acetonitrile; at 20 ℃; for 24h;
DOI:10.1002/ejoc.200800041

Reference yield: 84.0%

: 1048364-46-0
2-[3,5-bis(trifluoromethyl)phenylsulfonyl]-N-methoxy-N-methylacetamide

: 89-98-5
2-chloro-benzaldehyde

: 701913-98-6
(2E)-3-(2-chlorophenyl)-N-methoxy-N-methylacrylamide

Guidance literature:: With tetrabutylammomium bromide; potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 18h; diastereospecific reaction; Inert atmosphere;
DOI:10.1002/ejoc.200800041

Reference yield: 82.0%

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 1048364-46-0
2-[3,5-bis(trifluoromethyl)phenylsulfonyl]-N-methoxy-N-methylacetamide

: 201164-14-9
(E)-N-methoxy-N-methyl-3-(4-(trifluoromethyl)phenyl)acrylamide

Guidance literature:: With tetrabutylammomium bromide; potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 18h; diastereospecific reaction; Inert atmosphere;
DOI:10.1002/ejoc.200800041