cis-4-nitrobenzoic acid 4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyl ester

Base Information

Chemical Name:cis-4-nitrobenzoic acid 4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyl ester
CAS No.:1394012-00-0
Molecular Formula:C₂₁H₁₉ClF₃N₃O₅
Molecular Weight:485.847
Hs Code.:

Synonyms:cis-4-nitrobenzoic acid 4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyl ester

Suppliers and Price of cis-4-nitrobenzoic acid 4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of cis-4-nitrobenzoic acid 4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of cis-4-nitrobenzoic acid 4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyl ester

There total 5 articles about cis-4-nitrobenzoic acid 4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 948303-89-7
cis-4-nitro-benzoic acid 4-amino-cyclohexyl ester

: 327-78-6
4-chloro-3-(trifluoromethyl)phenyl isocyanate

: 1394012-00-0
cis-4-nitrobenzoic acid 4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyl ester

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 0 ℃; Inert atmosphere;

Reference yield:

: 62-23-7
4-nitro-benzoic acid

: 1394012-00-0
cis-4-nitrobenzoic acid 4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 20 °C / Inert atmosphere

2: hydrazine hydrate / dichloromethane; methanol / 20 °C / Inert atmosphere

3: triethylamine / N,N-dimethyl-formamide / 0 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; hydrazine hydrate; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 478832-23-4
cis-4-nitrobenzoic acid 4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)cyclohexyl ester

: 1394012-00-0
cis-4-nitrobenzoic acid 4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / dichloromethane; methanol / 20 °C / Inert atmosphere

2: triethylamine / N,N-dimethyl-formamide / 0 °C / Inert atmosphere

With hydrazine hydrate; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;