SULFAMIC ACID 2-(4-BROMO-PHENYL)-ETHYL ESTER

Base Information

• Chemical Name: SULFAMIC ACID 2-(4-BROMO-PHENYL)-ETHYL ESTER
• CAS No.: 120506-64-1
• Molecular Formula: C8H10 Br N O3 S
• Molecular Weight: 280.142
• Mol file: 120506-64-1.mol

Synonyms:4-Bromophenethylsulfamate

Chemical Property of SULFAMIC ACID 2-(4-BROMO-PHENYL)-ETHYL ESTER

Chemical Property:

• PSA: 77.77000
• LogP: 2.99280

Purity/Quality:

97% ^*data from raw suppliers

SULFAMIC ACID 2-(4-BROMO-PHENYL)-ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of SULFAMIC ACID 2-(4-BROMO-PHENYL)-ETHYL ESTER

There total 2 articles about SULFAMIC ACID 2-(4-BROMO-PHENYL)-ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromophenethanol (4654-39-1) + sulphamoyl chloride (7778-42-9) → 4-bromophenethyl sulfamate (120506-64-1)

Guidance literature:

In N,N-dimethyl-formamide;

Reference yield:

isocyanate de chlorosulfonyle (1189-71-5) + 4-bromophenethanol (4654-39-1) → 4-bromophenethyl sulfamate (120506-64-1)

Guidance literature:

isocyanate de chlorosulfonyle; With formic acid; In dichloromethane; at 0 - 20 ℃; for 9h;

4-bromophenethanol; With pyridine; In dichloromethane; at 20 ℃; for 4h;

DOI:10.1021/ja3122526

Reference yield: 87.0%

4-bromophenethyl sulfamate (120506-64-1) → 4-(4-bromo-phenyl)-[1,2,3]oxathiazolidine 2,2-dioxide

Guidance literature:

With [bis(acetoxy)iodo]benzene; [Fe^II(2,2’:6’,2’’:6’’,2’’’:6’’’,2’’’’-quinquepyridine)(CH3CN)₂](ClO₄)₂; magnesium oxide; In acetonitrile; at 80 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ja3122526

upstream raw materials:

4-bromophenethanol

sulphamoyl chloride

isocyanate de chlorosulfonyle

Refernces

• 1、 -. "Anticonvulsant phenethyl sulfamates". . . Retrieved 2008/06/13.