2-[5-(2,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine

Base Information

Chemical Name:2-[5-(2,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS No.:339103-05-8
Molecular Formula:C₁₃H₇Cl₂N₃O
Molecular Weight:292.124
Hs Code.:
DSSTox Substance ID:DTXSID101203507
ChEMBL ID:CHEMBL2164557

Synonyms:2-[5-(2,4-dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine;339103-05-8;JY-2;CHEMBL2164557;5-(2,4-dichlorophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole;Bionet2_000951;DTXSID101203507;HMS1366L05;BDBM50395932;STK185549;AKOS000643347;8K-369S;HY-153347;CS-0694028;SR-01000501763;SR-01000501763-1;Z57056184

Suppliers and Price of 2-[5-(2,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-[5-(2,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:290.9966172
Heavy Atom Count:19
Complexity:308

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=NC(=C1)C2=NOC(=N2)C3=C(C=C(C=C3)Cl)Cl

Technology Process of 2-[5-(2,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine

There total 4 articles about 2-[5-(2,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1772-01-6
(Z)-N'-hydroxy-pyridine-2-carboxamidine

: 89-75-8
2,4-dichlorobenzoyl chloride

: 339103-05-8
5-(2,4-dichlorophenyl)-3-(pyridin-2-yl)-1,2,4-oxadiazole

Guidance literature:: With pyridine; at 20 - 175 ℃; for 5h;

Reference yield:

: 100-70-9,1232006-36-8
2-Cyanopyridine

: 339103-05-8
5-(2,4-dichlorophenyl)-3-(pyridin-2-yl)-1,2,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium hydroxide / ethanol

2: dichloromethane

With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; dichloromethane;
DOI:10.1016/j.bmcl.2012.08.100

Reference yield:

: 50-84-0
2,4 dichlorobenzoic acid

: 339103-05-8
5-(2,4-dichlorophenyl)-3-(pyridin-2-yl)-1,2,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane

2: dichloromethane

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1016/j.bmcl.2012.08.100