cinnamoyl-N,N-diethylthiourea

Base Information

• Chemical Name: cinnamoyl-N,N-diethylthiourea
• CAS No.: 78374-78-4
• Molecular Formula: C₁₄H₁₈N₂OS
• Molecular Weight: 262.376
• Mol file: 78374-78-4.mol

Synonyms:cinnamoyl-N,N-diethylthiourea

Chemical Property of cinnamoyl-N,N-diethylthiourea

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cinnamoyl-N,N-diethylthiourea

There total 2 articles about cinnamoyl-N,N-diethylthiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

trans-3-Phenylpropenoyl isothiocyanate (75861-69-7) + diethylamine (109-89-7) → N,N-diethyl-N'-3-phenylpropenoylthiourea (78374-78-4)

Guidance literature:

In cyclohexane;

Reference yield: 62.0%

ammonium thiocyanate (1147550-11-5) + diethylamine (109-89-7) + Cinnamoyl chloride (102-92-1,17082-09-6) → cinnamoyl-N,N-diethylthiourea (78374-78-4)

Guidance literature:

ammonium thiocyanate; Cinnamoyl chloride; In acetone; at 50 ℃; for 1h;

diethylamine; In acetone; for 2h; Reflux;

DOI:10.1002/zaac.202100063

Reference yield: 88.0%

cobalt(II) diacetate tetrahydrate (6147-53-1) + cinnamoyl-N,N-diethylthiourea (78374-78-4) → C42H51CoN6O3S3

Guidance literature:

cobalt(II) diacetate tetrahydrate; cinnamoyl-N,N-diethylthiourea; In methanol; at 20 ℃; for 0.25h;

With sodium acetate; In methanol; at 40 ℃; for 1h;

DOI:10.1002/zaac.202100063

upstream raw materials:

trans-3-Phenylpropenoyl isothiocyanate

diethylamine

ammonium thiocyanate

Cinnamoyl chloride

Downstream raw materials:

2-Diethylamino-5-[1-phenyl-meth-(Z)-ylidene]-thiazol-4-one

2-Diethylamino-6-phenyl-5,6-dihydro-[1,3]thiazin-4-one